Weight loss at first postoperative visit predicts long-term outcome of Roux-en-Y gastric bypass using Duke weight loss surgery chart

Alessandro Mor, Lindsey Sharp, Dana Portenier, Ranjan Sudan, Alfonso Torquati, Alessandro Mor, Lindsey Sharp, Dana Portenier, Ranjan Sudan, Alfonso Torquati

Abstract

Background: Roux-en-Y gastric bypass has been used for >3 decades. However, no normative data are available to aid the bariatric surgeon in assessing the adequacy of weight loss at each postoperative visit. The objective of the present study was to construct nomograms to aid in the assessment of weight loss. The setting was a university hospital in the United States.

Methods: We used data prospectively collected from 1216 patients who had undergone Roux-en-Y gastric bypass at Duke University from April 2000 to September 2007. The percentage of excess weight loss (%EWL) was determined at each follow-up visit (1, 3, 6, 12, and 36 mo). The %EWL velocity was also determined using the postoperative data collected at the 1- and 3-month visits. Multivariate analysis was used to determine the predictive factors that influence the long-term results.

Results: At 12 months of follow-up, most patients, especially those in the first and fourth quartiles (P = .01), continued to be in the same weight loss quartile they had initially been in at 1 month postoperatively. The positive and negative predictive value for the first quartile %EWL at 1 month resulting in a first quartile %EWL at 12 months was 39% and 81%, respectively. Multivariate analysis indicated that gender, preoperative body mass index, %EWL at 1 month, and %EWL velocity were statistically significant predictors of the %EWL at 12 months postoperatively.

Conclusion: We are the first group to determine that weight loss performance in the early period is a significant predictor of the long-term outcomes. The clinical utility of the weight loss chart is to identify underperformers early in the postoperative period to potentially improve their outcomes.

Conflict of interest statement

Conflict of Interest Statement: All authors do not have any conflict of interest with an institution or product that is mentioned in the manuscript and/or is important to the outcome of the study presented.

Copyright © 2012 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved.

Figures

Figure 1
Figure 1
Relative contribution to the quartile at 12 and 36 months respectively.
Figure 2
Figure 2
Weight loss chart for preoperative body mass index (BMI)

Figure 3

Weight loss chart for preoperative…

Figure 3

Weight loss chart for preoperative body mass index (BMI) ≥ 50. Total number…

Figure 3
Weight loss chart for preoperative body mass index (BMI) ≥ 50. Total number of patients at 1, 3, 6, 9, 12 and 36 months are respectively 485, 434, 464, 471, 114.
Figure 3
Figure 3
Weight loss chart for preoperative body mass index (BMI) ≥ 50. Total number of patients at 1, 3, 6, 9, 12 and 36 months are respectively 485, 434, 464, 471, 114.

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