Diabetes 2030: Insights from Yesterday, Today, and Future Trends

William R Rowley, Clement Bezold, Yasemin Arikan, Erin Byrne, Shannon Krohe, William R Rowley, Clement Bezold, Yasemin Arikan, Erin Byrne, Shannon Krohe

Abstract

To forecast future trends in diabetes prevalence, morbidity, and costs in the United States, the Institute for Alternative Futures has updated its diabetes forecasting model and extended its projections to 2030 for the nation, all states, and several metropolitan areas. This paper describes the methodology and data sources for these diabetes forecasts and discusses key implications. In short, diabetes will remain a major health crisis in America, in spite of medical advances and prevention efforts. The prevalence of diabetes (type 2 diabetes and type 1 diabetes) will increase by 54% to more than 54.9 million Americans between 2015 and 2030; annual deaths attributed to diabetes will climb by 38% to 385,800; and total annual medical and societal costs related to diabetes will increase 53% to more than $622 billion by 2030. Improvements in management reducing the annual incidence of morbidities and premature deaths related to diabetes over this time period will result in diabetes patients living longer, but requiring many years of comprehensive management of multiple chronic diseases, resulting in dramatically increased costs. Aggressive population health measures, including increased availability of diabetes prevention programs, could help millions of adults prevent or delay the progression to type 2 diabetes, thereby helping turn around these dire projections.

Conflict of interest statement

Author Disclosure Statement Drs. Rowley and Bezold, and Ms. Arikan, Ms. Byrne, and Ms. Krohe declared the following conflicts of interest with respect to the research, authorship, and/or publication of this article: Dr. Rowley, Dr. Bezold, and Ms. Arikan are employed by the Institute for Alternative Futures (IAF), an independent nonprofit futures institute. IAF has received grants in the past from many health care organizations and pharmaceutical industry clients for health futures work. None of the 3 authors receive any other compensation from Novo Nordisk; they have no conflict of interest issues to report. Ms. Byrne and Ms. Krohe are employees of Novo Nordisk Inc. They reviewed all drafts of the methodology, the generated diabetes data, and the manuscripts that were developed and written by Dr. Rowley, Dr. Bezold, and Ms. Arikan. They provided their suggestions. The authors received the following financial support for this article: Funding for this study was provided by Novo Nordisk Inc.

Figures

FIG. 1.
FIG. 1.
Prevalence of total diabetes as a percent of total population for each state for 2015, 2020, 2025, and 2030 based on the Diabetes 2030 Model (age adjusted to standard population).

References

    1. Gregg EW, Li Y, Wang J, et al. . Changes in diabetes-related complications in the United States, 1990–2010. N Engl J Med 2014;370:1514–1523
    1. Centers for Disease Control and Prevention. National diabetes statistics report: Estimates of diabetes and its burden in the United States, 2014. Available at: <>. Accessed February6, 2015
    1. Institute for Alternative Futures. IAF Diabetes 2030 Model statistics for the United States, all states and several metropolitan areas. Available at: <>
    1. Rowley WR, Bezold C. Creating public awareness: State 2025 diabetes forecasts. Pop Health Manag 2012;15:194–200
    1. Boyle JP, Thompson TJ, Gregg EW, Barker LE, Williamson DF. Projection of the year 2050 burden of diabetes in the US adult population: Dynamic modeling of incidence, mortality and prediabetes prevalence. Popul Health Metr 2010;8:29.
    1. Geiss LS, Wang J, Cheng YJ, et al. . Prevalence and incidence trends for diagnosed diabetes among adults aged 20 to 79 years, United States, 1980–2012. JAMA 2014;312:1218–1226
    1. Abraham TM, Pencina KM, Pencina MJ, Fox CS. Trends in diabetes incidence: The Framingham heart study. Diabetes Care 2015;38(3):482–487
    1. Centers for Disease Control and Prevention. National diabetes fact sheet: United States, 2005. Available at: <>. Accessed February6, 2015
    1. Centers for Disease Control and Prevention. National diabetes fact sheet, 2007. Available at: <>. Accessed February6, 2015
    1. Centers for Disease Control and Prevention. National diabetes fact sheet, 2011. Available at: <>. Accessed February6, 2015
    1. Dall TM, Yang W, Halder P, et al. . The economic burden of elevated blood glucose levels in 2012: Diagnosed and undiagnosed diabetes, gestational diabetes mellitus, and prediabetes. Diabetes Care 2014;37:3172–3179
    1. United States Census Bureau. 2012 national population projections. 2015–2060 summary tables 2 and 4. Available at: <>. Accessed February4, 2015
    1. United States Census Bureau. 2005 interim state population projections, 2000–2030, tables A1 and B1. Available at: <>. Accessed February4, 2015
    1. Demographia. United States metropolitan areas: 2030 population projections. Available at: <>. Accessed February4, 2015
    1. Bizjournals. Projected population of 250 U.S. metros. Available at: <>. Accessed July30, 2010, for original study (no longer available online)
    1. Centers for Disease Control and Prevention, Diabetes Public Health Resource. Crude and age-adjusted percentage of adults aged 18 years or older with diagnosed diabetes reporting visual impairment, United States, 1997–2011. Available at: <>. Accessed February4, 2015
    1. Centers for Disease Control and Prevention, Diabetes Public Health Resource. Crude and age-adjusted incidence of end-stage renal disease related to diabetes mellitus (ESRD-DM) per 100,000 diabetic population, United /States, 1980–2008. Available at: <>. Accessed February4, 2015
    1. Centers for Disease Control and Prevention, Diabetes Public Health Resource. Crude and age-adjusted hospital discharge rates for nontraumatic lower extremity amputation per 1,000 diabetic population, United States, 1988–2009. Available at: <>. Accessed February4, 2015
    1. National Vital Statistics Reports; Death: Final data for 2000 = NVSR Vol. 50 No. 16; 2001 = NVSR Vol. 52 No. 9; 2002 = NVSR Vol. 53 No. 5; 2003 = NVSR Vol. 54 No. 13; 2004 = NVSR Vol. 55 No. 19; 2005 = NVSR Vol. 56. No. 10; 2006 = NVSR Vol. 57 No. 14; 2007 = NVSR Vol. 58 No. 19; 2008 = NVSR Vol. 59 No. 10; 2009 = NVSR Vol. 60 No. 3; 2010 = Vol. 61 No. 4. Available at: <>. Accessed February5, 2015
    1. United States Census Bureau. 2008 national population projections. Summary table 2: Projections of the population by selected age groups and sex for the United States: 2010 to 2050. Available at: <>. Accessed March15, 2015
    1. Ogden CL, Carroll MD, Fryar CD, Flegel KM. Prevalence of obesity among adults and youth: United States, 2011–2014. NCHS data brief, No. 219, 2015. Available at: <>. Accessed November15, 2015
    1. Menke A, Rust KF, Fradkin J, Cheng YJ, Cowie CC. Associations between trends in race/ethnicity, aging, and body mass index with diabetes prevalence in the United States: A series of cross-sectional studies. Ann Intern Med 2014;161:328–335
    1. Gregg EW, Cheng YJ, Saydah S, et al. . Trends in death rates among U.S. adults with and without diabetes between 1997 and 2006: Findings from the National Health Interview Survey. Diabetes Care 2012;35:1252–1257
    1. Gregg EW, Zhuo X, Cheng YJ, Albright AL, Narayan KMV, Thompson TJ. Trends in lifetime risk and years of life lost due to diabetes in the USA 1985–2011: A modelling study. Lancet Diabetes Endocrinol 2014;2:867–874
    1. The Diabetes Control and Complications Trial Research Group. Effect of intensive diabetes management on macrovascular events and risk factors in the diabetes control and complications trial. Am J Cardiol 1995;75:894–903
    1. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998;317:703–713
    1. UK Prospective Diabetes Study Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837–853
    1. Gaede P, Vedel P, Larsen N, Jensen GVH, Parving HH, Pedersen O. Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. N Engl J Med 2003;348:383–393
    1. Ali MK, Bullard KM, Saaddine JB, Cowie CC, Imperatore G, Gregg EW. Achievement of goals in U.S. diabetes care, 1999–2010. N Engl J Med 2013;368:1613–1624
    1. Cramer JA. A systematic review of adherence with medications for diabetes. Diabetes Care 2004;27:1218–1224
    1. Li R, Shrestha SS, Lipman R, Burrows NR, Kolb LE, Rutledge S. Diabetes self-management education and training among privately insured persons with newly diagnosed diabetes—United States, 2011–2012. MMWR 2014;63(46):1045–1049
    1. Pinhas-Hamiel O, Zeitler P. The global spread of type 2 diabetes mellitus in children and adolescents. J Pediatr 2005;146:693–700
    1. Cefalu WT, Petersen MP, Ratner RE. The alarming and rising costs of diabetes and prediabetes: A call for action! Diabetes Care 2014;37:3137–3138
    1. Zhuo X, Zhang P, Kahn HS, Bardenheier BH, Li R, Gregg EW. Change in medical spending attributable to diabetes: National data from 1987 to 2011. Diabetes Care 2015;38:581–587
    1. Dennis B. Prescription drug prices jumped more than 10 percent in 2015, analysis finds. Washington Post January 11, 2016. Available at: <>. Accessed February12, 2016
    1. Andrews M. High cost of diabetes drugs often goes overlooked. NPR August 18, 2015. Available at: <>. Accessed February12, 2016
    1. Siu AL, on behalf of the U.S. Preventive Services Task Force. Screening for abnormal blood glucose and type 2 diabetes mellitus: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2015;163:861–868
    1. Centers for Disease Control and Prevention. National Diabetes Prevention Program. Available at: <>. Accessed March16, 2015

Source: PubMed

Подписаться