How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over

Fiona F Stanaway, Danijela Gnjidic, Fiona M Blyth, David G Le Couteur, Vasi Naganathan, Louise Waite, Markus J Seibel, David J Handelsman, Philip N Sambrook, Robert G Cumming, Fiona F Stanaway, Danijela Gnjidic, Fiona M Blyth, David G Le Couteur, Vasi Naganathan, Louise Waite, Markus J Seibel, David J Handelsman, Philip N Sambrook, Robert G Cumming

Abstract

Objective: To determine the speed at which the Grim Reaper (or Death) walks.

Design: Population based prospective study.

Setting: Older community dwelling men living in Sydney, Australia.

Participants: 1705 men aged 70 or more participating in CHAMP (Concord Health and Ageing in Men Project).

Main outcome measures: Walking speed (m/s) and mortality. Receiver operating characteristics curve analysis was used to calculate the area under the curve for walking speed and determine the walking speed of the Grim Reaper. The optimal walking speed was estimated using the Youden index (sensitivity + specificity-1), a common summary measure of the receiver operating characteristics curve, and represents the maximum potential effectiveness of a marker.

Results: The mean walking speed was 0.88 (range 0.15-1.60) m/s. The highest Youden index (0.293) was observed at a walking speed of 0.82 m/s (2 miles (about 3 km) per hour), corresponding to a sensitivity of 63% and a specificity of 70% for mortality. Survival analysis showed that older men who walked faster than 0.82 m/s were 1.23 times less likely to die (95% confidence interval 1.10 to 1.37) than those who walked slower (P = 0.0003). A sensitivity of 1.0 was obtained when a walking speed of 1.36 m/s (3 miles (about 5 km) per hour) or greater was used, indicating that no men with walking speeds of 1.36 m/s or greater had contact with Death.

Conclusion: The Grim Reaper's preferred walking speed is 0.82 m/s (2 miles (about 3 km) per hour) under working conditions. As none of the men in the study with walking speeds of 1.36 m/s (3 miles (about 5 km) per hour) or greater had contact with Death, this seems to be the Grim Reaper's most likely maximum speed; for those wishing to avoid their allotted fate, this would be the advised walking speed.

Conflict of interest statement

Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; and no other relationships or activities that could appear to have influenced the submitted work.

Figures

https://www.ncbi.nlm.nih.gov/pmc/articles/instance/4788326/bin/staf001153.f1_default.jpg
Receiver operating characteristics curve for mortality over five years in relation to walking speed. *Optimal point identified by Youden index
https://www.ncbi.nlm.nih.gov/pmc/articles/instance/4788326/bin/gnjidic.f1_default.jpg

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Source: PubMed

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