Respiratory Allergens from Furred Mammals: Environmental and Occupational Exposure

Eva Zahradnik, Monika Raulf, Eva Zahradnik, Monika Raulf

Abstract

Furry mammals kept as pets, farm and laboratory animals are important allergen sources. The prevalence of sensitization to furred mammals appears to be increasing worldwide. Several mammalian allergens from diverse species are well characterized with regard to their molecular structure and immunogenicity, and some are already available for component-resolved allergy diagnostics. The distribution of various mammalian allergens has been extensively studied during the past few decades. Animal allergens were found to be ubiquitous in the human environment, even in places where no animals reside, with concentrations differing considerably between locations and geographical regions. This review presents an overview of identified mammalian respiratory allergens classified according to protein families, and compiles the results of allergen exposure assessment studies conducted in different public and occupational environments.

Keywords: allergen exposure; animal allergens; cat; cattle; dog; horse; mouse; rat.

Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Frequency of cat and dog ownership in different countries (based on Global GfK survey [3]).

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Source: PubMed

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