High prevalence of diagnosis of diabetes, depression, anxiety, hypertension, asthma and COPD in the total population of Stockholm, Sweden - a challenge for public health

Axel C Carlsson, Per Wändell, Urban Ösby, Ramin Zarrinkoub, Björn Wettermark, Gunnar Ljunggren, Axel C Carlsson, Per Wändell, Urban Ösby, Ramin Zarrinkoub, Björn Wettermark, Gunnar Ljunggren

Abstract

Background: There is limited knowledge on the prevalence of disease in total populations. Such studies have historically been difficult to conduct but the development of health data registers has facilitated large-scale studies on recorded diagnoses in entire regions. The aim of this study was to analyze the prevalence of diagnosis of six common diseases in the Swedish capital region.

Methods: The study population included all living persons who resided in Stockholm County, Sweden, on December 31st 2011 (N=2 093 717). Information on all consultations between 2007 and 2011 was obtained from primary health care, specialist outpatient care and inpatient care. Prevalence was defined as the proportion of individuals with a recorded diagnosis of diabetes, depression, anxiety disorders, hypertension, asthma and chronic obstructive pulmonary disease during the five year period, respectively. Analyses were done by age and gender.

Results: Hypertension had the highest five-year prevalence (12.2%), followed by depression (6.6%), diabetes mellitus (6.2%), asthma (5.9%), anxiety disorders/phobia (4.8%), and COPD (1.8%). Diabetes was more common in men (5.3% of women and 7.1% of men) while depression (8.7% in women and 4.4% in men) and anxiety (6.3% in women and 3.4% in men) were considerably more common in women. Smaller gender differences were also found for hypertension (13.0% in women and 11.4% in men), asthma (6.4% in women and 5.4% in men) and COPD (2.1% in women and 1.6% in men). Diabetes, hypertension and COPD increased markedly with age, whereas anxiety, depression and asthma were fairly constant in individuals above 18 years. During one year of observation, more than half of all patients had only been diagnosed in primary health care, with hypertension being the diagnosis with the largest proportion of patients only identified in primary health care (70.6%).

Conclusion: The prevalence of common diseases in the population can be estimated by combining data gathered during consecutive years from primary care, specialist outpatient care and inpatient care. However, accuracy of disease prevalence is highly dependent on the quality of the data. The high prevalence of the six diagnoses analysed in this study calls for preventive action to minimize suffering and costs to society.

References

    1. Wandell PE, Johansson SE, Gafvels C, Hellenius ML, de Faire U, Sundquist J. Estimation of diabetes prevalence among immigrants from the Middle East in Sweden by using three different data sources. Diabetes Metab. 2008;34(4 Pt 1):328–333.
    1. Rodriguez EM, Staffa JA, Graham DJ. The role of databases in drug postmarketing surveillance. Pharmacoepidemiol Drug Saf. 2001;10(5):407–410. doi: 10.1002/pds.615.
    1. Sweden S. Statistical yearbook of Sweden 2011. Stockholm: Statistics Sweden; 2010.
    1. Ludvigsson JF, Andersson E, Ekbom A, Feychting M, Kim JL, Reuterwall C, Heurgren M, Olausson PO. External review and validation of the Swedish national inpatient register. BMC Publ Health. 2011;11:450. doi: 10.1186/1471-2458-11-450.
    1. Rosen M. National health data registers: a Nordic heritage to public health. Scand J Public Health. 2002;30(2):81–85.
    1. Nilsson G, Ahlfeldt H, Strender LE. Textual content, health problems and diagnostic codes in electronic patient records in general practice. Scand J Prim Health Care. 2003;21(1):33–36. doi: 10.1080/02813430310000537.
    1. Wirehn AB, Karlsson HM, Carstensen JM. Estimating disease prevalence using a population-based administrative healthcare database. Scand J Public Health. 2007;35(4):424–431. doi: 10.1080/14034940701195230.
    1. Sorensen HT, Sabroe S, Olsen J. A framework for evaluation of secondary data sources for epidemiological research. Int J Epidemiol. 1996;25(2):435–442. doi: 10.1093/ije/25.2.435.
    1. Ekman I, Wolf A, Olsson LE, Taft C, Dudas K, Schaufelberger M, Swedberg K. Effects of person-centred care in patients with chronic heart failure: the PCC-HF study. Eur Heart J. 2012;33(9):1112–1119. doi: 10.1093/eurheartj/ehr306.
    1. Burstrom B. Will Swedish healthcare reforms affect equity? BMJ. 2009;339:b4566. doi: 10.1136/bmj.b4566.
    1. Lofgren S, Ljunggren G, Brommels M. No ticking time bomb: hospital utilisation of 28,528 hip fracture patients in Stockholm during 1998–2007. Scand J Public Health. 2010;38(4):418–425. doi: 10.1177/1403494810370232.
    1. Rydholm A, Ljunggren G, Grafström M, Strömberg L. Dementia, delirium and other co-morbid conditions in acute hip fracture care – traditions, attitudes and local policies rather than actual state guide diagnose making? Vårdi Norden. 2005;25(4):25–29.
    1. Lokk J, Borg S, Svensson J, Persson U, Ljunggren G. Drug and treatment costs in Parkinson’s disease patients in Sweden. ActaNeurol Scand. 2012;125(2):142–147.
    1. Carlsson AC, Wandell PE, de Faire U, Hellenius ML. Prevalence of hypertension in immigrants and Swedish-born individuals, a cross-sectional study of 60-year-old men and women in Sweden. J Hypertens. 2008;26(12):2295–2302. doi: 10.1097/HJH.0b013e32831391c3.
    1. Wandell PE, Carlsson AC, de Faire U, Hellenius ML. Prevalence of blood lipid disturbances in Swedish and foreign-born 60-year-old men and women in Stockholm, Sweden. NutrMetab Cardiovasc Dis. 2011;21(3):173–181. doi: 10.1016/j.numecd.2009.09.007.
    1. Carlsson AC, Theobald H, Wandell PE. Health factors and longevity in men and women: a 26-year follow-up study. Eur J Epidemiol. 2010;25(8):547–551. doi: 10.1007/s10654-010-9472-2.
    1. Nilsson J, Ostling S, Waern M, Karlsson B, Sigstrom R, Guo X, Skoog I. The 1-month prevalence of generalized anxiety disorder according to DSM-IV, DSM-V, and ICD-10 among nondemented 75-year-olds in Gothenburg, Sweden. Am J Geriatr Psychiatry. 2012;20(11):963–972. doi: 10.1097/JGP.0b013e318252e749.
    1. Wallerblad A, Moller J, Forsell Y. Care-seeking pattern among persons with depression and anxiety: a population-based study in Sweden. Int J Family Med. 2012;2012:895425.
    1. Wandell PE, Gafvels C. Patients with type 2 diabetes aged 35–64 years at four primary health care centres in Stockholm County, Sweden. Prevalence and complications in relation to gender and socio-economic status. Diabetes Res Clin Pract. 2004;63(3):195–203. doi: 10.1016/j.diabres.2003.08.011.
    1. Gale EA, Gillespie KM. Diabetes and gender. Diabetologia. 2001;44(1):3–15. doi: 10.1007/s001250051573.
    1. Jansson SP, Andersson DK, Svardsudd K. Prevalence and incidence rate of diabetes mellitus in a Swedish community during 30 years of follow-up. Diabetologia. 2007;50(4):703–710. doi: 10.1007/s00125-007-0593-4.
    1. Wandell PE, Carlsson A, Steiner KH. Prevalence of diabetes among immigrants in the Nordic countries. Curr Diabetes Rev. 2010;6(2):126–133. doi: 10.2174/157339910790909404.
    1. Patten SB, Stuart HL, Russell ML, Maxwell CJ, Arboleda-Florez J. Epidemiology of major depression in a predominantly rural health region. Soc Psychiatry Psychiatr Epidemiol. 2003;38(7):360–365.
    1. Andersson D, Magnusson H, Carstensen J, Borgquist L. Co-morbidity and health care utilisation five years prior to diagnosis for depression. A register-based study in a Swedish population. BMC Publ Health. 2011;11:552. doi: 10.1186/1471-2458-11-552.
    1. Egan BM, Zhao Y, Axon RN. US trends in prevalence, awareness, treatment, and control of hypertension, 1988–2008. JAMA. 2010;303(20):2043–2050. doi: 10.1001/jama.2010.650.
    1. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365(9455):217–223.
    1. Joffres MR, Hamet P, MacLean DR, L'Italien GJ, Fodor G. Distribution of blood pressure and hypertension in Canada and the United States. Am J Hypertens. 2001;14(1 Pt 1):1099–1105.
    1. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S. et al.2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC) Eur Heart J. 2007;28(12):1462–1536.
    1. Vasan RS, Beiser A, Seshadri S, Larson MG, Kannel WB, D'Agostino RB, Levy D. Residual lifetime risk for developing hypertension in middle-aged women and men: the Framingham heart study. JAMA. 2002;287(8):1003–1010. doi: 10.1001/jama.287.8.1003.
    1. Marques-Vidal P, Tuomilehto J. Hypertension awareness, treatment and control in the community: is the ‘rule of halves’ still valid? J Hum Hypertens. 1997;11(4):213–220. doi: 10.1038/sj.jhh.1000426.
    1. Wolf-Maier K, Cooper RS, Banegas JR, Giampaoli S, Hense HW, Joffres M, Kastarinen M, Poulter N, Primatesta P, Rodriguez-Artalejo F. et al.Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA. 2003;289(18):2363–2369. doi: 10.1001/jama.289.18.2363.
    1. Anandan C, Nurmatov U, van Schayck OC, Sheikh A. Is the prevalence of asthma declining? Systematic review of epidemiological studies. Allergy. 2010;65(2):152–167. doi: 10.1111/j.1398-9995.2009.02244.x.
    1. Osborne ML, Vollmer WM, Linton KL, Buist AS. Characteristics of patients with asthma within a large HMO: a comparison by age and gender. Am J Respir Crit Care Med. 1998;157(1):123–128. doi: 10.1164/ajrccm.157.1.9612063.
    1. Weiner P, Magadle R, Massarwa F, Beckerman M, Berar-Yanay N. Influence of gender and inspiratory muscle training on the perception of dyspnea in patients with asthma. Chest. 2002;122(1):197–201. doi: 10.1378/chest.122.1.197.
    1. Ballardini N, Kull I, Lind T, Hallner E, Almqvist C, Ostblom E, Melen E, Pershagen G, Lilja G, Bergstrom A. et al.Development and comorbidity of eczema, asthma and rhinitis to age 12: data from the BAMSE birth cohort. Allergy. 2012;67(4):537–544. doi: 10.1111/j.1398-9995.2012.02786.x.
    1. Wandell PE, Carlsson AC, Sundquist K, Johansson SE, Sundquist J. Total mortality among levothyroxine-treated women with atrial fibrillation in Swedish primary health care. Int J Cardiol. 2011;152(1):147–148. doi: 10.1016/j.ijcard.2011.07.066.
    1. Hjerpe P, Merlo J, Ohlsson H, Bengtsson Bostrom K, Lindblad U. Validity of registration of ICD codes and prescriptions in a research database in Swedish primary care: a cross-sectional study in Skaraborg primary care database. BMC Med Inform Decis Mak. 2010;10:23. doi: 10.1186/1472-6947-10-23.
    1. Forrest CB. Primary care in the United States: primary care gatekeeping and referrals: effective filter or failed experiment? BMJ. 2003;326(7391):692–695. doi: 10.1136/bmj.326.7391.692.
    1. Nazir A, Papita R, Anbalagan VP, Anjana RM, Deepa M, Mohan V. Prevalence of diabetes in Asian Indians based on glycated hemoglobin and fasting and 2-h post-load (75-g) plasma glucose (CURES-120) Diabetes Technol Ther. 2012;14(8):665–668. doi: 10.1089/dia.2012.0059.

Source: PubMed

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