Energy balance and obesity: what are the main drivers?

Isabelle Romieu, Laure Dossus, Simón Barquera, Hervé M Blottière, Paul W Franks, Marc Gunter, Nahla Hwalla, Stephen D Hursting, Michael Leitzmann, Barrie Margetts, Chizuru Nishida, Nancy Potischman, Jacob Seidell, Magdalena Stepien, Youfa Wang, Klaas Westerterp, Pattanee Winichagoon, Martin Wiseman, Walter C Willett, IARC working group on Energy Balance and Obesity, Isabelle Romieu, Laure Dossus, Simón Barquera, Hervé M Blottière, Paul W Franks, Marc Gunter, Nahla Hwalla, Stephen D Hursting, Michael Leitzmann, Barrie Margetts, Chizuru Nishida, Nancy Potischman, Jacob Seidell, Magdalena Stepien, Youfa Wang, Klaas Westerterp, Pattanee Winichagoon, Martin Wiseman, Walter C Willett, IARC working group on Energy Balance and Obesity

Abstract

Purpose: The aim of this paper is to review the evidence of the association between energy balance and obesity.

Methods: In December 2015, the International Agency for Research on Cancer (IARC), Lyon, France convened a Working Group of international experts to review the evidence regarding energy balance and obesity, with a focus on Low and Middle Income Countries (LMIC).

Results: The global epidemic of obesity and the double burden, in LMICs, of malnutrition (coexistence of undernutrition and overnutrition) are both related to poor quality diet and unbalanced energy intake. Dietary patterns consistent with a traditional Mediterranean diet and other measures of diet quality can contribute to long-term weight control. Limiting consumption of sugar-sweetened beverages has a particularly important role in weight control. Genetic factors alone cannot explain the global epidemic of obesity. However, genetic, epigenetic factors and the microbiota could influence individual responses to diet and physical activity.

Conclusion: Energy intake that exceeds energy expenditure is the main driver of weight gain. The quality of the diet may exert its effect on energy balance through complex hormonal and neurological pathways that influence satiety and possibly through other mechanisms. The food environment, marketing of unhealthy foods and urbanization, and reduction in sedentary behaviors and physical activity play important roles. Most of the evidence comes from High Income Countries and more research is needed in LMICs.

Keywords: Diet; Energy balance; Energy expenditure; Energy intake; Obesity; Satiety.

Figures

Fig. 1
Fig. 1
Prevalence of obesity, ages 18+, both sexes, 2014 (age-standardized estimates)—source: WHO

References

    1. Anderson AS, Key TJ, Norat T, Scoccianti C, Cecchini M, Berrino F et al. European code against cancer 4th edition: obesity, body fatness and cancer. Cancer Epidemiol. 2015
    1. World Health Organization (2014) Global status report on noncommunicable diseases: World Health Organization, Geneva.
    1. World Cancer Research Fund/American Institute for Cancer Research . Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington DC: AICR; 2007.
    1. World Cancer Research Fund/American Institute for Cancer Research (2009) Policy and action for cancer prevention. Food, nutrition, and physical activity: a global perspective
    1. Ng M, Fleming T, Robinson M, Thomson B, Graetz N, Margono C, et al. Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2014;384(9945):766–781. doi: 10.1016/S0140-6736(14)60460-8.
    1. de Onis M, Blossner M, Borghi E. Global prevalence and trends of overweight and obesity among preschool children. Am J Clin Nutr. 2010;92(5):1257–1264. doi: 10.3945/ajcn.2010.29786.
    1. Lobstein T, Jackson-Leach R, Moodie ML, Hall KD, Gortmaker SL, Swinburn BA, et al. Child and adolescent obesity: part of a bigger picture. Lancet. 2015;385(9986):2510–2520. doi: 10.1016/S0140-6736(14)61746-3.
    1. Wabitsch M, Moss A, Kromeyer-Hauschild K. Unexpected plateauing of childhood obesity rates in developed countries. BMC Med. 2014;12:17. doi: 10.1186/1741-7015-12-17.
    1. Wang YF, Baker JL, Hil JO, Dietz WH. Controversies regarding reported trends: has the obesity epidemic leveled off in the United States? Adv Nutr. 2012;3(5):751–752. doi: 10.3945/an.112.002790.
    1. United Nations Children’s Fund World Health Organization, The World Bank. Levels and trends in child malnutrition UNICEF–WHO–World Bank Group joint child malnutrition estimates: key findings of the 2015 edition 2015. .
    1. Shrimpton R, Rokx C. The double burden of malnutrition : a review of global evidence. Health, Nutrition and Population (HNP) discussion paper. Washington DC: World Bank; 2012.
    1. Darnton-Hill I, Nishida C, James WP. A life course approach to diet, nutrition and the prevention of chronic diseases. Public Health Nutr. 2004;7(1a):101–121. doi: 10.1079/PHN2003584.
    1. James P et al (2000). Ending malnutrition by 2020: an agenda for change in the Millennium. UN SCN, Geneva
    1. Moubarac JC, Martins AP, Claro RM, Levy RB, Cannon G, Monteiro CA. Consumption of ultra-processed foods and likely impact on human health. Evidence from Canada. Public Health Nutr. 2013;16(12):2240–2248. doi: 10.1017/S1368980012005009.
    1. Monteiro CA, Levy RB, Claro RM, de Castro IR, Cannon G. Increasing consumption of ultra-processed foods and likely impact on human health: evidence from Brazil. Public Health Nutr. 2011;14(1):5–13. doi: 10.1017/S1368980010003241.
    1. Baker P, Friel S. Processed foods and the nutrition transition: evidence from Asia. Obes Rev. 2014;15(7):564–577. doi: 10.1111/obr.12174.
    1. Barquera S, Pedroza-Tobias A, Medina C. Cardiovascular diseases in mega-countries: the challenges of the nutrition, physical activity and epidemiologic transitions, and the double burden of disease. Curr Opin Lipidol. 2016;27(4):329–344. doi: 10.1097/MOL.0000000000000320.
    1. International Food Policy Research Institute (2015). Global nutrition report 2015: actions and accountability to advance nutrition and sustainable development. Washington, DC
    1. Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K, et al. Body fatness and cancer–viewpoint of the IARC Working Group. N Engl J Med. 2016;375(8):794–798. doi: 10.1056/NEJMsr1606602.
    1. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–674. doi: 10.1016/j.cell.2011.02.013.
    1. Bonomini F, Rodella LF, Rezzani R. Metabolic syndrome, aging and involvement of oxidative stress. Aging disease. 2015;6(2):109–120. doi: 10.14336/AD.2014.0305.
    1. Hursting SD, Berger NA. Energy balance, host-related factors, and cancer progression. J Clin Oncol. 2010;28(26):4058–4065. doi: 10.1200/JCO.2010.27.9935.
    1. Renehan AG, Roberts DL, Dive C. Obesity and cancer: pathophysiological and biological mechanisms. Arch Physiol Biochem. 2008;114(1):71–83. doi: 10.1080/13813450801954303.
    1. Sun Q, van Dam RM, Spiegelman D, Heymsfield SB, Willett WC, Hu FB. Comparison of dual-energy X-ray absorptiometric and anthropometric measures of adiposity in relation to adiposity-related biologic factors. Am J Epidemiol. 2010;172(12):1442–1454. doi: 10.1093/aje/kwq306.
    1. World Health Organization (2011) Waist circumference and waist-hip ratio: a report of a WHO expert consultation
    1. van der Kooy K, Leenen R, Seidell JC, Deurenberg P, Droop A, Bakker CJ. Waist-hip ratio is a poor predictor of changes in visceral fat. Am J Clin Nutr. 1993;57(3):327–333.
    1. Willett W. Implications of total energy intake for epidemiologic analyses. Nutritional epidemiology. 3rd edn. Oxford University Press, New York, pp 260–286
    1. Heymsfield SB, Lohman TG, Wang Z, Going SB (2005) Human body composition. 2nd edn. Champaign
    1. McCrory MA, Gomez TD, Bernauer EM, Mole PA. Evaluation of a new air displacement plethysmograph for measuring human body composition. Med Sci Sports Exerc. 1995;27(12):1686–1691. doi: 10.1249/00005768-199512000-00016.
    1. Glickman SG, Marn CS, Supiano MA, Dengel DR. Validity and reliability of dual-energy X-ray absorptiometry for the assessment of abdominal adiposity. J Appl Physiol (1985) 2004;97(2):509–514. doi: 10.1152/japplphysiol.01234.2003.
    1. Bandera EV, Maskarinec G, Romieu I, John EM. Racial and ethnic disparities in the impact of obesity on breast cancer risk and survival: a global perspective. Adv Nutr. 2015;6(6):803–819. doi: 10.3945/an.115.009647.
    1. Scientific Advisory Committee on Nutrition . Dietary reference values for energy. London: The Stationery Office; 2011.
    1. Hall KD, Sacks G, Chandramohan D, Chow CC, Wang YC, Gortmaker SL, et al. Quantification of the effect of energy imbalance on bodyweight. Lancet. 2011;378(9793):826–837. doi: 10.1016/S0140-6736(11)60812-X.
    1. Healy GN, Wijndaele K, Dunstan DW, Shaw JE, Salmon J, Zimmet PZ, et al. Objectively measured sedentary time, physical activity, and metabolic risk: the Australian Diabetes, Obesity and Lifestyle Study (AusDiab) Diabetes Care. 2008;31(2):369–371. doi: 10.2337/dc07-1795.
    1. Romero-Corral A, Somers VK, Sierra-Johnson J, Thomas RJ, Collazo-Clavell ML, Korinek J, et al. Accuracy of body mass index in diagnosing obesity in the adult general population. Int J Obes (Lond) 2008;32(6):959–966. doi: 10.1038/ijo.2008.11.
    1. Ello-Martin JA, Ledikwe JH, Rolls BJ (2005) The influence of food portion size and energy density on energy intake: implications for weight management. Am J Clin Nutr 82(1 Suppl):236 S–241 S
    1. Prentice AM (1998) Manipulation of dietary fat and energy density and subsequent effects on substrate flux and food intake. Am J Clin Nutr 67(3 Suppl):535 S–541 S
    1. Fogelholm M, Anderssen S, Gunnarsdottir I, Lahti-Koski M (2012) Dietary macronutrients and food consumption as determinants of long-term weight change in adult populations: a systematic literature review. Food Nutr Res 56
    1. Salas-Salvado J, Bullo M, Babio N, Martinez-Gonzalez MA, Ibarrola-Jurado N, Basora J, et al. Reduction in the incidence of type 2 diabetes with the Mediterranean diet: results of the PREDIMED-Reus nutrition intervention randomized trial. Diabetes Care. 2011;34(1):14–19. doi: 10.2337/dc10-1288.
    1. Jaworowska A, Blackham T, Davies IG, Stevenson L. Nutritional challenges and health implications of takeaway and fast food. Nutr Rev. 2013;71(5):310–318. doi: 10.1111/nure.12031.
    1. Schroder H, Fito M, Covas MI. Association of fast food consumption with energy intake, diet quality, body mass index and the risk of obesity in a representative Mediterranean population. Br J Nutr. 2007;98(6):1274–1280. doi: 10.1017/S0007114507781436.
    1. Pereira MA, Kartashov AI, Ebbeling CB, Van Horn L, Slattery ML, Jacobs DR, Jr, et al. Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis. Lancet. 2005;365(9453):36–42. doi: 10.1016/S0140-6736(04)17663-0.
    1. Alkerwi A, Crichton GE, Hebert JR (2014) Consumption of ready-made meals and increased risk of obesity: findings from the observation of cardiovascular risk factors in Luxembourg (ORISCAV-LUX) study. Br J Nutr 1–8
    1. Kant AK, Whitley MI, Graubard BI. Away from home meals: associations with biomarkers of chronic disease and dietary intake in American adults, NHANES 2005–2010. Int J Obes (Lond) 2015;39(5):820–827. doi: 10.1038/ijo.2014.183.
    1. Chajes V, Biessy C, Ferrari P, Romieu I, Freisling H, Huybrechts I, et al. Plasma elaidic acid level as biomarker of industrial trans fatty acids and risk of weight change: report from the EPIC study. PloS one. 2015;10(2):e0118206. doi: 10.1371/journal.pone.0118206.
    1. Han E, Powell LM. Consumption patterns of sugar-sweetened beverages in the United States. J Acad Nutr Dietetics. 2013;113(1):43–53. doi: 10.1016/j.jand.2012.09.016.
    1. Basu S, McKee M, Galea G, Stuckler D. Relationship of soft drink consumption to global overweight, obesity, and diabetes: a cross-national analysis of 75 countries. Am J Public Health. 2013;103(11):2071–2077. doi: 10.2105/AJPH.2012.300974.
    1. Malik VS, Pan A, Willett WC, Hu FB. Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis. Am J Clin Nutr. 2013;98(4):1084–1102. doi: 10.3945/ajcn.113.058362.
    1. Te Morenga L, Mallard S, Mann J. Dietary sugars and body weight: systematic review and meta-analyses of randomised controlled trials and cohort studies. BMJ. 2013;346:e7492. doi: 10.1136/bmj.e7492.
    1. Rouhani MH, Salehi-Abargouei A, Surkan PJ, Azadbakht L. Is there a relationship between red or processed meat intake and obesity? A systematic review and meta-analysis of observational studies. Obes Rev. 2014;15(9):740–748. doi: 10.1111/obr.12172.
    1. Fung TT, Pan A, Hou T, Chiuve SE, Tobias DK, Mozaffarian D, et al. Long-term change in diet quality is associated with body weight change in men and women. J Nutr. 2015;145(8):1850–1856. doi: 10.3945/jn.114.208785.
    1. Romaguera D, Norat T, Vergnaud AC, Mouw T, May AM, Agudo A, et al. Mediterranean dietary patterns and prospective weight change in participants of the EPIC-PANACEA project. Am J Clin Nutr. 2010;92(4):912–921. doi: 10.3945/ajcn.2010.29482.
    1. Funtikova AN, Benitez-Arciniega AA, Gomez SF, Fito M, Elosua R, Schroder H. Mediterranean diet impact on changes in abdominal fat and 10-year incidence of abdominal obesity in a Spanish population. Br J Nutr. 2014;111(8):1481–1487. doi: 10.1017/S0007114513003966.
    1. Buckland G, Bach A, Serra-Majem L. Obesity and the Mediterranean diet: a systematic review of observational and intervention studies. Obes Rev Off J Int Assoc Study Obes. 2008;9(6):582–593. doi: 10.1111/j.1467-789X.2008.00503.x.
    1. Richter LM, Victora CG, Hallal PC, Adair LS, Bhargava SK, Fall CH, et al. Cohort profile: the consortium of health-orientated research in transitioning societies. Int J Epidemiol. 2012;41(3):621–626. doi: 10.1093/ije/dyq251.
    1. Lajous M, Ortiz-Panozo E, Monge A, Santoyo-Vistrain R, Garcia-Anaya A, Yunes-Diaz E et al (2015) Cohort Profile: The Mexican Teachers’ Cohort (MTC). Int J Epidemiol
    1. Romieu I, Escamilla-Nunez MC, Sanchez-Zamorano LM, Lopez-Ridaura R, Torres-Mejia G, Yunes EM, et al. The association between body shape silhouette and dietary pattern among Mexican women. Public Health Nutr. 2012;15(1):116–125. doi: 10.1017/S1368980011001182.
    1. Scientific Advisory Committee on Nutrition . Carbohydrates and health. London: The Stationery Office; 2015.
    1. Mirza NM, Palmer MG, Sinclair KB, McCarter R, He J, Ebbeling CB, et al. Effects of a low glycemic load or a low-fat dietary intervention on body weight in obese Hispanic American children and adolescents: a randomized controlled trial. Am J Clin Nutr. 2013;97(2):276–285. doi: 10.3945/ajcn.112.042630.
    1. Tobias DK, Chen M, Manson JE, Ludwig DS, Willett W, Hu FB. Effect of low-fat diet interventions versus other diet interventions on long-term weight change in adults: a systematic review and meta-analysis. Lancet Diabetes. Endocrinol. 2015;3(12):968–979.
    1. Hu T, Mills KT, Yao L, Demanelis K, Eloustaz M, Yancy WS, Jr, et al. Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. Am J Epidemiol. 2012;176(Suppl 7):S44–S54. doi: 10.1093/aje/kws264.
    1. Donnelly JE, Blair SN, Jakicic JM, Manore MM, Rankin JW, Smith BK, et al. American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009;41(2):459–471. doi: 10.1249/MSS.0b013e3181949333.
    1. Thorogood A, Mottillo S, Shimony A, Filion KB, Joseph L, Genest J, et al. Isolated aerobic exercise and weight loss: a systematic review and meta-analysis of randomized controlled trials. Am J Med. 2011;124(8):747–755. doi: 10.1016/j.amjmed.2011.02.037.
    1. Miller CT, Fraser SF, Levinger I, Straznicky NE, Dixon JB, Reynolds J, et al. The effects of exercise training in addition to energy restriction on functional capacities and body composition in obese adults during weight loss: a systematic review. PloS one. 2013;8(11):e81692. doi: 10.1371/journal.pone.0081692.
    1. Ismail I, Keating SE, Baker MK, Johnson NA. A systematic review and meta-analysis of the effect of aerobic vs. resistance exercise training on visceral fat. Obes Rev Off J Int Assoc Study Obesity. 2012;13(1):68–91. doi: 10.1111/j.1467-789X.2011.00931.x.
    1. Schwingshackl L, Dias S, Strasser B, Hoffmann G. Impact of different training modalities on anthropometric and metabolic characteristics in overweight/obese subjects: a systematic review and network meta-analysis. PLoS One. 2013;8(12):e82853. doi: 10.1371/journal.pone.0082853.
    1. Hu FB, Li TY, Colditz GA, Willett WC, Manson JE. Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. Jama. 2003;289(14):1785–1791. doi: 10.1001/jama.289.14.1785.
    1. Liao Y, Liao J, Durand CP, Dunton GF. Which type of sedentary behaviour intervention is more effective at reducing body mass index in children? A meta-analytic review. Obes Rev Off J Int Assoc Study Obesity. 2014;15(3):159–168. doi: 10.1111/obr.12112.
    1. Blundell JE, Gibbons C, Caudwell P, Finlayson G, Hopkins M. Appetite control and energy balance: impact of exercise. ObesRev. 2015;16(Suppl 1):67–76.
    1. Franks PW, Ravussin E, Hanson RL, Harper IT, Allison DB, Knowler WC, et al. Habitual physical activity in children: the role of genes and the environment. Am J Clin Nutr. 2005;82(4):901–908.
    1. Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197–206. doi: 10.1038/nature14177.
    1. Ahmad S, Varga TV, Franks PW. Gene x environment interactions in obesity: the state of the evidence. Hum Hered. 2013;75(2–4):106–115. doi: 10.1159/000351070.
    1. Kilpelainen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, et al. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med. 2011;8(11):e1001116. doi: 10.1371/journal.pmed.1001116.
    1. Qi Q, Chu AY, Kang JH, Jensen MK, Curhan GC, Pasquale LR, et al. Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med. 2012;367(15):1387–1396. doi: 10.1056/NEJMoa1203039.
    1. Franks PW, Christophi CA, Jablonski KA, Billings LK, Delahanty LM, Horton ES, et al. Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program. Diabetologia. 2014;57(3):485–490. doi: 10.1007/s00125-013-3133-4.
    1. Nettleton JA, Follis JL, Ngwa JS, Smith CE, Ahmad S, Tanaka T, et al. Gene x dietary pattern interactions in obesity: analysis of up to 68,317 adults of European ancestry. Hum Mol Genet. 2015;24(16):4728–4738. doi: 10.1093/hmg/ddv186.
    1. van Dijk SJ, Tellam RL, Morrison JL, Muhlhausler BS, Molloy PL. Recent developments on the role of epigenetics in obesity and metabolic disease. Clinical Epigenetics. 2015;7(1):66. doi: 10.1186/s13148-015-0101-5.
    1. Chambers JC, Loh M, Lehne B, Drong A, Kriebel J, Motta V et al. Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case–control study. Lancet Diabetes Endocrinol 3(7):526–534
    1. Dick KJ, Nelson CP, Tsaprouni L, Sandling JK, Aïssi D, Wahl S et al. DNA methylation and body-mass index: a genome-wide analysis. Lancet. 383(9933):1990–1998
    1. Blottiere HM, de Vos WM, Ehrlich SD, Dore J. Human intestinal metagenomics: state of the art and future. Curr Opin Microbiol. 2013;16(3):232–239. doi: 10.1016/j.mib.2013.06.006.
    1. Vangay P, Ward T, Gerber JS, Knights D. Antibiotics, pediatric dysbiosis, and disease. Cell Host Microbe. 2015;17(5):553–564. doi: 10.1016/j.chom.2015.04.006.
    1. Le Chatelier E, Nielsen T, Qin J, Prifti E, Hildebrand F, Falony G, et al. Richness of human gut microbiome correlates with metabolic markers. Nature. 2013;500(7464):541–546. doi: 10.1038/nature12506.
    1. Dao MC, Everard A, Aron-Wisnewsky J, Sokolovska N, Prifti E, Verger EO, et al. Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology. Gut. 2016;65(3):426–436. doi: 10.1136/gutjnl-2014-308778.
    1. Kong LC, Holmes BA, Cotillard A, Habi-Rachedi F, Brazeilles R, Gougis S, et al. Dietary patterns differently associate with inflammation and gut microbiota in overweight and obese subjects. PLoS One. 2014;9(10):e109434. doi: 10.1371/journal.pone.0109434.
    1. Lobstein T, Baur L, Uauy R, TaskForce IIO. Obesity in children and young people: a crisis in public health. Obes Rev. 2004;5(Suppl 1):4–104. doi: 10.1111/j.1467-789X.2004.00133.x.
    1. Perez-Morales E, Bacardi-Gascon M, Jimenez-Cruz A. Sugar-sweetened beverage intake before 6 years of age and weight or BMI status among older children; systematic review of prospective studies. Nutr Hosp. 2013;28(1):47–51.
    1. Robinson TN. Reducing children’s television viewing to prevent obesity: a randomized controlled trial. JAMA. 1999;282(16):1561–1567. doi: 10.1001/jama.282.16.1561.
    1. Fatima Y, Doi SAR, Mamun AA. Longitudinal impact of sleep on overweight and obesity in children and adolescents: a systematic review and bias-adjusted meta-analysis. Obes Rev. 2015;16(2):137–149. doi: 10.1111/obr.12245.
    1. Lobstein T, Jackson-Leach R, Moodie ML, Hall KD, Gortmaker SL, Swinburn BA et al (2015) Child and adolescent obesity: part of a bigger picture. Lancet
    1. WHO (2004) Global strategy on diet, physical activity and health—what are the causes? World Health Organization
    1. ISDOHaD. International Society for Developmental Origins of Health and Disease
    1. Tie HT, Xia YY, Zeng YS, Zhang Y, Dai CL, Guo JJ, et al. Risk of childhood overweight or obesity associated with excessive weight gain during pregnancy: a meta-analysis. Arch Gynecol Obstet. 2014;289(2):247–257. doi: 10.1007/s00404-013-3053-z.
    1. Norris SA, Osmond C, Gigante D, Kuzawa CW, Ramakrishnan L, Lee NR, et al. Size at birth, weight gain in infancy and childhood, and adult diabetes risk in five low- or middle-income country birth cohorts. Diabetes Care. 2012;35(1):72–79. doi: 10.2337/dc11-0456.
    1. Adair LS, Martorell R, Stein AD, Hallal PC, Sachdev HS, Prabhakaran D, et al. Size at birth, weight gain in infancy and childhood, and adult blood pressure in 5 low- and middle-income-country cohorts: when does weight gain matter? Am J Clin Nutr. 2009;89(5):1383–1392. doi: 10.3945/ajcn.2008.27139.
    1. de Beer M, Vrijkotte TG, Fall CH, van Eijsden M, Osmond C, Gemke RJ. Associations of infant feeding and timing of linear growth and relative weight gain during early life with childhood body composition. Int J Obes (Lond) 2015;39(4):586–592. doi: 10.1038/ijo.2014.200.
    1. Papadimitriou A. Timing of adiposity rebound and prevalence of obesity. J Pediatr. 2015;167(2):498. doi: 10.1016/j.jpeds.2015.04.072.
    1. Weng SF, Redsell SA, Swift JA, Yang M, Glazebrook CP. Systematic review and meta-analyses of risk factors for childhood overweight identifiable during infancy. Arch Dis Child. 2012;97(12):1019–1026. doi: 10.1136/archdischild-2012-302263.
    1. Pearce J, Taylor MA, Langley-Evans SC. Timing of the introduction of complementary feeding and risk of childhood obesity: a systematic review. Int J Obesity. 2013;37(10):1295–1306. doi: 10.1038/ijo.2013.99.
    1. Wilson SM, Sato AF. Stress and paediatric obesity: what we know and where to go Stress. Health (London) 2014;30(2):91–102.
    1. Cecchini M, Sassi F, Lauer JA, Lee YY, Guajardo-Barron V, Chisholm D. Tackling of unhealthy diets, physical inactivity, and obesity: health effects and cost-effectiveness. Lancet. 376(9754):1775–1784
    1. Gortmaker SL, Long MW, Resch SC, Ward ZJ, Cradock AL, Barrett JL, et al. Cost effectiveness of childhood obesity interventions: evidence and methods for CHOICES. Am J Prev Med. 2015;49(1):102–111. doi: 10.1016/j.amepre.2015.03.032.
    1. Pan American Health Organization . Recommendations from a Pan American Health Organization Expert Consultation on the Marketing of Food and Non-Alcoholic Beverages to Children in the Americas. Washington, D.C.: PAHO; 2011.
    1. Jenkin G, Madhvani N, Signal L, Bowers S. A systematic review of persuasive marketing techniques to promote food to children on television. Obes Rev. 2014;15(4):281–293. doi: 10.1111/obr.12141.
    1. Hawkes C. Regulating and litigating in the public interest: regulating food marketing to young people worldwide: trends and policy drivers. Am J Public Health. 2007;97(11):1962–1973. doi: 10.2105/AJPH.2006.101162.
    1. Wang YWY, Wilson RF, Bleich S, Cheskin L, Weston C, Showell N, Fawole O, Lau B, Segal J (2013) Childhood obesity prevention programs: comparative effectiveness review and meta-analysis internet: agency for healthcare research and quality (US); 2013. Contract No.: 13-EHC081-EF
    1. USDA Nutrition Evidence Library (NEL) (2014) Dietary patterns systematic review
    1. UK Scientific Advisory Committee on Nutrition (2011) The influence of maternal, fetal and child nutrition on development of chronic disease in later life
    1. Emmett PM, Jones LR. Diet, growth, and obesity development throughout childhood in the Avon Longitudinal Study of Parents and Children. Nutr Rev. 2015;73(Suppl 3):175–206. doi: 10.1093/nutrit/nuv054.
    1. Victora CG, Adair L, Fall C, Hallal PC, Martorell R, Richter L, et al. Maternal and child undernutrition: consequences for adult health and human capital. Lancet. 2008;371(9609):340–357. doi: 10.1016/S0140-6736(07)61692-4.
    1. Yang Z, Huffman SL. Nutrition in pregnancy and early childhood and associations with obesity in developing countries. Matern Child Nutr. 2013;9(Suppl 1):105–119. doi: 10.1111/mcn.12010.
    1. Michels KB, Willett WC, Graubard BI, Vaidya RL, Cantwell MM, Sansbury LB, et al. A longitudinal study of infant feeding and obesity throughout life course. Int J Obes (Lond) 2007;31(7):1078–1085. doi: 10.1038/sj.ijo.0803622.
    1. Ramirez-Silva I, Rivera JA, Trejo-Valdivia B, Martorell R, Stein AD, Romieu I, et al. Breastfeeding status at age 3 months is associated with adiposity and cardiometabolic markers at age 4 years in Mexican children. J Nutr. 2015;145(6):1295–1302. doi: 10.3945/jn.114.198366.

Source: PubMed

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