Potential applications of topical oxygen therapy in dermatology
Luigi Bennardo, Ester Del Duca, Stefano Dastoli, Giusy Schipani, Elisabetta Scali, Martina Silvestri, Steven P Nisticò, Luigi Bennardo, Ester Del Duca, Stefano Dastoli, Giusy Schipani, Elisabetta Scali, Martina Silvestri, Steven P Nisticò
Abstract
Background: Topical oxygen therapy is a cosmetic procedure that is becoming more and more popular in dermatology; however, only a few articles on this topic are present in the literature. In this work we report our group experience with oxygen therapy as an adjuvant treatment in various dermatological conditions.
Methods: Four studies were conducted. In the first study we used vehiculated oxygen therapy for diseases that cause hair loss. In the second study oxygen was used in the treatment of mild acne. In the third study moderate acne was treated with topical oxygen. In the fourth study chronic dermatological conditions such as psoriasis and atopic dermatitis were treated with this procedure.
Results: In studies 1 and 2 the outcomes in groups who used topical oxygen therapy as an adjuvant treatment were better than in the groups that did not use it. Studies 3 and 4 also showed very good results, but no control groups were present in the study.
Conclusion: Topical oxygen therapy was useful in the treatment of hair loss conditions, mild and moderate acne, and in chronic cutaneous diseases, showing effectiveness as a support therapy in all of these conditions. Further and larger studies should be conducted to better evaluate its effectiveness in dermatological conditions.
Keywords: acne; chronic dermatosis; hair loss; oxygen; topical oxygen therapy.
Conflict of interest statement
Competing interests: The authors have no conflicts of interest to disclose.
References
- Grainge C. Breath of life: the evolution of oxygen therapy. J R Soc Med. 2004;97(10):489–493.
- Barr PO, Enfors W, Eriksson G. Hyperbaric oxygen therapy in dermatology. Br J Dermatol. 1972;86(6):631–635.
- Asadamongkol B, Zhang JH. The development of hyperbaric oxygen therapy for skin rejuvenation and treatment of photoaging. Med Gas Res. 2014;4(1):7.
- Sheridan RL, Shank ES. Hyperbaric oxygen treatment: a brief overview of a controversial topic. J Trauma. 1999;47(2):426–435.
- Gill AL, Bell CN. Hyperbaric oxygen: its uses, mechanisms of action and outcomes. QJM. 2004;97(7):385–395.
- Edwards ML. Hyperbaric oxygen therapy part 2: application in disease. J Vet Emerg Crit Care. 2010;20(3):289–297.
- Cheung EJ, Sink JR, English JC., III Vitamin and mineral deficiencies in patients with telogen effluvium: a retrospective cross-sectional study. J Drugs Dermatol. 2016;15(10):1235–1237.
- Ellis JA, Sinclair R, Harrap SB. Androgenetic alopecia: pathogenesis and potential for therapy. Expert Rev Mol Med. 2002;4(22):1–11.
- Siah TW, Muir-Green L, Shapiro J. Female Pattern hair loss: a retrospective study in a tertiary referral center. Int J Trichology. 2016;8(2):57–61.
- Hordinsky MK. Medical treatment of noncicatricial alopecia. Semin Cutan Med Surg. 2006;25(1):51–55.
- Price VH. Treatment of hair loss. N Engl J Med. 1999;341(13):964–973.
- Picardo M, Eichenfield LF, Tan J. Acne and rosacea. Dermatol Ther (Heidelb) 2017;7(Suppl 1):43–52.
- Bhat YJ, Latief I, Hassan I. Update on etiopathogenesis and treatment of acne. Indian J Dermatol Venereol Leprol. 2017;83(3):298–306.
- Abo El-Fetoh NM, Alenezi NG, Alshamari NG, Alenezi OG. Epidemiology of acne vulgaris in adolescent male students in Arar, Kingdom of Saudi Arabia. J Egypt Public Health Assoc. 2016;91(3):144–149.
- Al-Natour SH. Acne vulgaris: perceptions and beliefs of Saudi adolescent males. J Family Community Med. 2017;24(1):34–43.
- Fife D. Evaluation of acne scars: how to assess them and what to tell the patient. Dermatol Clin. 2016;34(2):207–213.
- Sugathan P. Current dermatological therapy: acne vulgaris—the boils of lust. Indian J Dermatol Venereol Leprol. 1979;45(2):148–153.
Source: PubMed