Evaluation of the effectiveness of combined femtosecond laser-assisted cataract surgery and femtosecond laser astigmatic keratotomy in improving post-operative visual outcomes

Jing Wang, Jiangyue Zhao, Jun Xu, Jinsong Zhang, Jing Wang, Jiangyue Zhao, Jun Xu, Jinsong Zhang

Abstract

Background: To determine postoperative refractive and visual outcomes and astigmatic changes after femtosecond laser astigmatic keratotomy in femtosecond laser-assisted cataract surgery (FLACS).

Methods: This was a prospective interventional case series. Patients with age-related cataract and corneal astigmatism (1.0-3.0D) were treated with FLACS and femtosecond laser astigmatic keratotomy (FSAK). All patients underwent examinations before and 3 months after surgery; visual acuity, subjective and objective refraction, and corneal astigmatism were evaluated and recorded for all patients by using an OPD-Scan III topographer. Vector analysis of astigmatic changes was performed by using the Alpins vector method.

Results: Twenty-five patients were included in the study. Postoperatively, refractive and corneal astigmatism were both reduced significantly (P < 0.05), concurrent with improved uncorrected distance visual acuity and corrected distance visual acuity. The rate of spectacle use was significantly reduced at 3 months postoperatively (P = 0.001). The mean magnitude of the target-induced astigmatism vector (1.40 ± 0.37D) was slightly higher than the mean magnitude of the surgically induced astigmatism vector (1.22 ± 0.46D). The magnitude of error (- 0.18 ± 0.36D), as well as the correction index (0.88 ± 0.29), demonstrated slight undercorrection. The angle of error was 0.85 ± 13.69°, which was close to zero.

Conclusions: Combined femtosecond laser-assisted cataract surgery and astigmatic keratotomy may be an effective approach to manage preoperative astigmatism in cataract surgery, although slight undercorrection may exist during short-term follow-up.

Trial registration: ChiCTR-TRC-14004977.

Keywords: Astigmatism; Effectiveness; Femtosecond laser astigmatic keratotomy; Femtosecond laser-assisted cataract surgery.

Conflict of interest statement

Ethics approval and consent to participate

This study was approved by the Institutional Ethical Committee of the Fourth Affiliated Hospital of China Medical University, Shenyang (No.: 2014-036). We confirm that written consent was obtained from all participants.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
An example of the programmed femtosecond laser-assisted astigmatic keratotomy in femtosecond laser assisted cataract surgery
Fig. 2
Fig. 2
The scatter plot of target induced astigmatism vs. surgically induced astigmatism
Fig. 3
Fig. 3
The angle of error was 0.85 ± 13.69°, indicating that the surgically induced astigmatism was counter-clockwise to the target induced astigmatism
Fig. 4
Fig. 4
The distribution of preoperative corneal astigmatism
Fig. 5
Fig. 5
The distribution of postoperative corneal astigmatism

References

    1. Miyake T, Kamiya K, Amano R, Iida Y, Tsunehiro S, Shimizu K. Long-term clinical outcomes of toric intraocular lens implantation in cataract cases with preexisting astigmatism. J Cataract Refract Surg. 2014;40(10):1654–1660. doi: 10.1016/j.jcrs.2014.01.044.
    1. Chen W, Zuo C, Chen C, Su J, Luo L, Congdon N, Liu Y. Prevalence of corneal astigmatism before cataract surgery in Chinese patients. J Cataract Refract Surg. 2013;39(2):188–192. doi: 10.1016/j.jcrs.2012.08.060.
    1. Mendicute J, Irigoyen C, Ruiz M, Illarramendi I, Ferrer-Blasco T, Montes-Mico R. Toric intraocular lens versus opposite clear corneal incisions to correct astigmatism in eyes having cataract surgery. J Cataract Refract Surg. 2009;35(3):451–458. doi: 10.1016/j.jcrs.2008.11.043.
    1. Nichamin LD. Treating astigmatism at the time of cataract surgery. Curr Opin Ophthalmol. 2003;14(1):35–38. doi: 10.1097/00055735-200302000-00006.
    1. Amesbury EC, Miller KM. Correction of astigmatism at the time of cataract surgery. Curr Opin Ophthalmol. 2009;20(1):19–24. doi: 10.1097/ICU.0b013e328319c27a.
    1. Fares U, Mokashi AA, Al-Aqaba MA, Otri AM, Miri A, Dua HS. Management of postkeratoplasty astigmatism by paired arcuate incisions with compression sutures. Br J Ophthalmol. 2013;97(4):438–443. doi: 10.1136/bjophthalmol-2012-302128.
    1. Lindstrom RL. The surgical correction of astigmatism: a clinician’s perspective. Refract Corneal Surg. 1990;6(6):441–454.
    1. Vickers LA, Gupta PK. Femtosecond laser-assisted keratotomy. Curr Opin Ophthalmol. 2016;27(4):277–284. doi: 10.1097/ICU.0000000000000267.
    1. Callou TP, Garcia R, Mukai A, Giacomin NT, de Souza RG, Bechara SJ. Advances in femtosecond laser technology. Clin Ophthalmol. 2016;10:697–703. doi: 10.2147/OPTH.S99741.
    1. Alpins NA, Goggin M. Practical astigmatism analysis for refractive outcomes in cataract and refractive surgery. Surv Ophthalmol. 2004;49(1):109–122. doi: 10.1016/j.survophthal.2003.10.010.
    1. Reinstein DZ, Archer TJ, Randleman JB. JRS standard for reporting astigmatism outcomes of refractive surgery. J Refract Surg. 2014;30(10):654–659. doi: 10.3928/1081597X-20140903-01.
    1. Krall EM, Arlt EM, Hohensinn M, Moussa S, Jell G, Alio JL, Plaza-Puche AB, Bascaran L, Mendicute J, Grabner G, et al. Vector analysis of astigmatism correction after toric intraocular lens implantation. J Cataract Refract Surg. 2015;41(4):790–799. doi: 10.1016/j.jcrs.2014.07.038.
    1. Titiyal JS, Khatik M, Sharma N, Sehra SV, Maharana PK, Ghatak U, Agarwal T, Khokhar S, Chawla B. Toric intraocular lens implantation versus astigmatic keratotomy to correct astigmatism during phacoemulsification. J Cataract Refract Surg. 2014;40(5):741–747. doi: 10.1016/j.jcrs.2013.10.036.
    1. Kessel L, Andresen J, Tendal B, Erngaard D, Flesner P, Hjortdal J. Toric intraocular lenses in the correction of astigmatism during cataract surgery: a systematic review and meta-analysis. Ophthalmology. 2016;123(2):275–286. doi: 10.1016/j.ophtha.2015.10.002.
    1. Inoue T, Maeda N, Sasaki K, Watanabe H, Inoue Y, Nishida K, Inoue Y, Yamamoto S, Shimomura Y, Tano Y. Factors that influence the surgical effects of astigmatic keratotomy after cataract surgery. Ophthalmology. 2001;108(7):1269–1274. doi: 10.1016/S0161-6420(01)00629-7.
    1. Yoo A, Yun S, Kim JY, Kim MJ, Tchah H. Femtosecond laser-assisted arcuate keratotomy versus toric IOL implantation for correcting astigmatism. J Refract Surg. 2015;31(9):574–578. doi: 10.3928/1081597X-20150820-01.
    1. Ng AL, Chan TC, Jhanji V, Cheng GP. Simple steep-axis marking technique using a corneal analyzer. J Cataract Refract Surg. 2017;43(2):153–155. doi: 10.1016/j.jcrs.2016.09.023.
    1. Muller-Jensen K, Fischer P, Siepe U. Limbal relaxing incisions to correct astigmatism in clear corneal cataract surgery. J Refract Surg. 1999;15(5):586–589.
    1. Day AC, Lau NM, Stevens JD. Nonpenetrating femtosecond laser intrastromal astigmatic keratotomy in eyes having cataract surgery. J Cataract Refract Surg. 2016;42(1):102–109. doi: 10.1016/j.jcrs.2015.07.045.
    1. Marino GK, Santhiago MR, Wilson SE. Femtosecond lasers and corneal surgical procedures. Asia Pac J Ophthalmol. 2017;6(5):456–464.
    1. Day AC, Stevens JD. Stability of keratometric astigmatism after non-penetrating femtosecond laser intrastromal astigmatic keratotomy performed during laser cataract surgery. J Refract Surg. 2016;32(3):152–155. doi: 10.3928/1081597X-20160204-01.
    1. Ruckl T, Dexl AK, Bachernegg A, Reischl V, Riha W, Ruckhofer J, Binder PS, Grabner G. Femtosecond laser-assisted intrastromal arcuate keratotomy to reduce corneal astigmatism. J Cataract Refract Surg. 2013;39(4):528–538. doi: 10.1016/j.jcrs.2012.10.043.
    1. Kim P, Sutton GL, Rootman DS. Applications of the femtosecond laser in corneal refractive surgery. Curr Opin Ophthalmol. 2011;22(4):238–244. doi: 10.1097/ICU.0b013e3283477c9c.
    1. Chan TC, Cheng GP, Wang Z, Tham CC, Woo VC, Jhanji V. Vector analysis of corneal astigmatism after combined femtosecond-assisted phacoemulsification and arcuate keratotomy. Am J Ophthalmol. 2015;160(2):250–255.e252. doi: 10.1016/j.ajo.2015.05.004.
    1. Rainer G, Menapace R, Vass C, Annen D, Findl O, Schmetterer K. Corneal shape changes after temporal and superolateral 3.0 mm clear corneal incisions. J Cataract Refract Surg. 1999;25(8):1121–1126. doi: 10.1016/S0886-3350(99)00132-7.
    1. Nejima R, Terada Y, Mori Y, Ogata M, Minami K, Miyata K. Clinical utility of femtosecond laser-assisted astigmatic keratotomy after cataract surgery. Jpn J Ophthalmol. 2015;59(4):209–215. doi: 10.1007/s10384-015-0383-3.
    1. Mayer WJ, Klaproth OK, Hengerer FH, Kook D, Dirisamer M, Priglinger S, Kohnen T. In vitro immunohistochemical and morphological observations of penetrating corneal incisions created by a femtosecond laser used for assisted intraocular lens surgery. J Cataract Refract Surg. 2014;40(4):632–638. doi: 10.1016/j.jcrs.2014.02.015.
    1. Hooshmand J, Vote BJ. Femtosecond laser-assisted cataract surgery, technology, outcome, future directions and modern applications. Asia Pac J Ophthalmol. 2017;6(4):393–400.
    1. Hura AS, Osher RH. Comparing the Zeiss Callisto Eye and the Alcon Verion image guided system toric lens alignment technologies. J Refract Surg. 2017;33(7):482–487. doi: 10.3928/1081597X-20170504-02.

Source: PubMed

Подписаться