Worse Prognosis in Heart Failure Patients with 30-Day Readmission

Ying-Chang Tung, Shing-Hsien Chou, Kuan-Liang Liu, I-Chang Hsieh, Lung-Sheng Wu, Chia-Pin Lin, Ming-Shien Wen, Pao-Hsien Chu, Ying-Chang Tung, Shing-Hsien Chou, Kuan-Liang Liu, I-Chang Hsieh, Lung-Sheng Wu, Chia-Pin Lin, Ming-Shien Wen, Pao-Hsien Chu

Abstract

Background: Heart failure (HF) readmission results in substantial expenditure on HF management. This study aimed to evaluate the readmission rate, outcome, and predictors of HF readmission.

Methods: Patients with reduced left ventricular ejection fraction (LVEF < 40%) who were admitted for acute decompensation of de novo HF were enrolled to analyze readmission rate, mortality and predictors of readmission.

Results: A total of 433 de novo HF patients with LVEF < 40% were enrolled during the period August 2013 to December 2014. The in-hospital and 6-month mortality rates were 3.9% and 15.2%, respectively. In those patients surviving the index HF hospitalization, the 30-day and 6-month readmission rates were 10.9% and 27%, respectively. At the end of the 6-month follow-up, the readmission group had higher mortality than the non-readmission group (27.66% vs. 10.36%; p = 0.001). The survivors of the 30-day readmission had similar mortality rates at 6 months, regardless of the cause of readmission (cardiovascular vs. non-cardiovascular: 25% vs. 30.43%, p = 0.677). Among all the parameters, prescription of beta blockers independently reduced the risk of 30-day readmission (odds ratio 0.15; 95% confidence interval 0.02-0.99; p = 0.049).

Conclusions: Those HF patients who suffered from 30-day readmission had worse prognosis at the 6-month follow-up. Regardless of the readmission causes, the patients surviving the 30-day readmission had similar mortality rates at 6-month follow-up. These results underscored the importance of reducing readmission as a means to improve HF outcome.

Keywords: Heart failure; Prognosis; Readmission.

Figures

Figure 1
Figure 1
Patient enrollment. ADHF, acute decompensated heart failure; HF, heart failure; LVEF, left ventricular ejection fraction.
Figure 2
Figure 2
Cardiovascular and non-cardiovascular readmissions during 6-month follow-up. CV, cardiovascular.
Figure 3
Figure 3
Kaplan-Meier survival analysis of readmission vs. non-readmission groups (A) and cardiovascular (CV) vs. non-CV causes of readmission (B).

Source: PubMed

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