Focused Versus Enhanced Cognitive Behavioral Therapy for Treating Women With Bulimia Nervosa
Treatment of Bulimia Nervosa: Dysregulated Subtype
研究概览
地位
条件
详细说明
Bulimia nervosa (BN) is a common eating disorder that is characterized by periods of bingeing and purging. People with the dysregulated subtype of BN experience behavioral impulsivity; disruption of cognitive, affective, behavioral, and neurophysiological processes (dysregulation); interpersonal dysfunction; and poor treatment response. To date, no therapies have been tested for this specific population, and it is unknown whether therapy that directly focuses on treating BN symptoms or one that addresses both eating and personality disorder symptoms is more effective. Cognitive behavioral therapy (CBT), which concentrates on modifying patients' behaviors and ways of thinking, has been effective in treating BN. This study will compare the effectiveness of two types of CBT, focused and broad, in treating adult women with the dysregulated subtype of BN.
Participants in this single-blind study will be randomly assigned to receive 20 sessions of either broad (enhanced) or focused CBT. Participants will meet with a therapist once or twice weekly until 20 sessions have occurred. Broad CBT will address symptoms of BN, as well as those of the personality disorder. Focused CBT will concentrate only on BN symptoms. Before treatment begins, participants will complete a set of questionnaires pertaining to their experiences with BN, depression, anxiety, and interpersonal relationships. The questionnaires will be used throughout the study to assess participants' progress. Participants will also attend a clinical interview lasting approximately 3.5 hours. Questions will concern BN, other eating disorder symptoms, depression, anxiety, and interpersonal relationships. Blood samples and vital signs will also be taken at the time of the clinical interview and as needed later in the treatment process.
研究类型
注册 (实际的)
阶段
- 阶段2
联系人和位置
学习地点
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Massachusetts
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Boston、Massachusetts、美国、02215
- Center for Anxiety and Related Disorders, Boston University
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Diagnosis of bulimia nervosa
- Presence of borderline personality disorder features
- History of one mood or anxiety episode within 2 years prior to study entry
- If taking psychiatric medication, dose has been stable for at least 6 weeks at time of study entry
Exclusion Criteria:
- Substance dependence
- Diagnosis of bipolar I disorder
- Psychosis
- Mental retardation
- Receiving psychosocial treatment
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:无(打开标签)
武器和干预
参与者组/臂 |
干预/治疗 |
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有源比较器:CBT-EF
Participants will receive cognitive behavioral therapy - focused
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Focused CBT concentrates only on BN symptoms.
There will be 20 sessions over the course of 5 months.
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实验性的:CBT-EB
Participants will receive cognitive behavioral therapy - broad
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Broad CBT addresses symptoms of BN, as well as those of the personality disorder.
CBT-EB incorporates ED interventions from CBT-EF but also has modules focused on addressing mood intolerance and interpersonal difficulties.
There will be 20 sessions over 5 months.
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研究衡量的是什么?
主要结果指标
结果测量 |
大体时间 |
---|---|
Eating disorder symptoms
大体时间:Measured throughout the study
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Measured throughout the study
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次要结果测量
结果测量 |
大体时间 |
---|---|
Depression symptoms
大体时间:Measured throughout the study
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Measured throughout the study
|
Anxiety symptoms
大体时间:Measured throughout the study
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Measured throughout the study
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Interpersonal relationships
大体时间:Measured throughout the study
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Measured throughout the study
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合作者和调查者
调查人员
- 首席研究员:Heather Thompson-Brenner, PhD、Center for Anxiety and Related Disorders, Boston University
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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