Methadone Maintenance Treatment Outcome Study in Taiwan (M0508)
Opioid abuse is a complex problem, which not only impacts on the affected individuals' physical and psychological health, but also threatens public security and the productivity of the society. Further, through needle sharing and sexual contacts, injecting drug users (IDUs) have become laden with HIV and HIV related health problems, representing a serious public health threat all over the world. In Taiwan, since the identification of the first HIV-infected IDU in 1987, the incident cases have continued to increase, reaching a height of 2,461 in 2005. In order to contain the epidemics of HIV among IDUs, and to prevent its spread to the population in general, the Center for Disease Control (CDC) collaborated with the Department of Justice to initiate and implement a number of harm reduction programs in 2005. The fact that opioid addiction is officially treated as a health rather than a legal issue itself represents a remarkable milestone in Taiwan. Among these harm reduction programs, including needle and syringe exchange for IDUs as well as substitution treatment approaches for opioid dependence, methadone maintenance treatment (MMT) perhaps represents the most most important and most crucial component. Remarkably, in a relatively short time span, more than 60 MMT programs were established, which enrolled more than 15,000 heroin addicts. This notwithstanding, the overall and differential effectiveness of these MMT service delivery systems, as well as the characteristics of these programs and the patients that might contribute toward treatment response or failure remain largely unknown. Such knowledge base is crucial for establishing standardized and feasible outcome evaluation processes for opioid addicts receiving MMT programs, as well as for the further improvement of the efficacy and effectiveness of these programs, in Taiwan.
In order to address some of these issues, this study adopts a multi-site, prospective clinical follow-up design. It aims at establishing a research network for examining MMT outcome, developing standardized MMT outcome assessment instruments and procedures, and identifying predictors of MMT outcome. The findings may contribute to the better understanding of the characteristics of opioid addicts, the effectiveness of MMT and remaining service needs for opioid addicts in Taiwan.
研究概览
地位
条件
研究类型
注册 (预期的)
联系人和位置
学习地点
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Miaoli、台湾
- 招聘中
- Departments of Psychiatry, Wei-Gong Memorial Hospital
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首席研究员：
- Ming-Lun Liu, MD
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接触：
- Ming-Lun Liu, MD
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Taichung、台湾
- 招聘中
- Departments of Psychiatry, China Medical University and Hospital
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首席研究员：
- Chieh-Liang Huang, MD
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接触：
- Chieh-Liang Huang, MD
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Taipei、台湾
- 招聘中
- Departments of Psychiatry, Taipei City Hospital Song-De Campus
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首席研究员：
- Lien-Wen Su, MD
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接触：
- Lien-Wen Su, MD
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Taipei、台湾
- 招聘中
- Departments of Psychiatry, Taipei City Hospital Yang-Ming Campus
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首席研究员：
- Yih-Hong Yang, MD
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副研究员：
- Yung-Chun Fang, MD
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接触：
- Yih-Hong Yang, MD
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Taipei、台湾
- 招聘中
- Departments of Psychiatry, Far-Eastern Memorial Hospital
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首席研究员：
- Chi-Shin Wu, MD
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副研究员：
- Kai-Chi Fang, MD
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接触：
- Chi-Shin Wu, MD
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Taipei County、台湾
- 招聘中
- Departments of Psychiatry, En-Chu-Kong Hospital
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首席研究员：
- Li-Nen Lin, MD
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副研究员：
- Yen-Feng Lin, MD
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接触：
- Li-Nen Lin, MD
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Tao-Yuan、台湾
- 招聘中
- Departments of Psychiatry, Tao-yuan Psychiatric Center
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接触：
- Happy Kuy-Lok Tan, MD, MPH
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首席研究员：
- Happy Kuy-Lok Tan, MD, MPH
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副研究员：
- Sun-Yuan Chou, MD
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副研究员：
- Kuen-Hong Wu, MD
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Be 18 years or older.
- Be fulfilling the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria of opiate dependence.
- Be agree to and capable of signing informed consent form that has been approved by an Institution Review Board.
Exclusion Criteria:
- Have ever participated in the study at one of the collaborative hospitals/clinics.
- Be expecting to discontinue methadone treatment for any reason (leaving the methadone clinic's geographic area, pending legal action, etc.) in the following 3 months.
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
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Heroin-addicted Patients
Heroin-addicted outpatient department (OPD) patients who seek help for methadone maintenance treatment
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合作者和调查者
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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