Artemether-Lumefantrine Effectiveness in Guinea-Bissau 2
The Routine Use of Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Bissau - 2
研究概览
地位
条件
详细说明
Children from Bissau seeking medical advice and who are recommended treatment for malaria in accordance with the current routines will be included as follows:
All children getting the clinical diagnosis of malaria will be registered and basic information collected.
All children with a positive malaria film and/or a positive RDT will be asked for a capillary blood sample (app. 50 - 100 microliters on a filterpaper). Using PCR the parasitological diagnosis will be verified and if parasites are identified the resistance patterns will be examined. Both the capillary blood samples and the RDTs (if taken by the health staff) will be used in order to examine whether the RDTs can be used for routine monitoring of resistance in an area.
The study does not interfere in the routine treatment of the health staff. None of the children will be followed.
研究类型
注册 (实际的)
联系人和位置
学习地点
-
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Bissau Codex
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Bissau、Bissau Codex、几内亚比绍
- Bandim Health Project
-
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Children seeking a health centre and by the health staff given the diagnosis: malaria and/or being treated with an antimalarial.
Exclusion Criteria:
- Children where the parents do not accept to participate in the study.
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Percentage of children treated for malaria with a parasitological confirmed malaria.
大体时间:6 weeks
|
The blood samples will be analysed for parasites at the end of the study.
The results do not have any impact on the treatment of the children.
|
6 weeks
|
次要结果测量
结果测量 |
大体时间 |
---|---|
Percentage of the parasites with mutations coding for resistance to antimalarials.
大体时间:2 years
|
2 years
|
合作者和调查者
调查人员
- 首席研究员:Poul-Erik Kofoed, MD, Ph.d.、Bandim Health Project
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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