Comparison of Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position
Comparison of Extent of Epidurography and Thoracic Epidural Pressure in the Prone and Lateral Decubitus Position
It is reported that the distribution of contrast medium had an obvious correlation with the extent of sensory analgesia after injection of LA. Our previous study showed that different posture (prone vs. lateral decubitus) resulted in different degree of contrast medium spread. We supposed that differences of epidural pressure between diverse postures might be one factor contributing those differences of epidurography.
This study was designed to compare the epidural pressure and extent of spread of epidurography between prone and lateral decubitus position
研究概览
详细说明
It is known that postoperative pain after thoracotomy or lobectomy is very severe, therefore, intraoperative or postoperative pain management using continuous thoracic epidural catheterization is suggested good option to prevent this potential complication.
The spread of local anesthetics is influenced by various factors including volume, location of needle insertion, speed of injection, patient position, age, weight and height. However, there are few studies about the effect of different patient position affeting the epidural pressure and the extent of spread of contrast medium during thoracic epidural catheterization.
Studies of lumbar epidural blockade have shown that lateral position can produce 0-3 segment more to the dependent position compared to the supine position. When the same amount of local anesthetic was injected in supine of sitting position, the most cephalad level of spread was indifferent. Recent studies showed that neck flexion demonstrated significant cephalad spread of contrast dye in high thoracic epidural blockade. The purpose of this study was to compare and evaluate the changes of epidural pressure with extent of spread of contrast medium between different posture
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Daegu、大韩民国、700712
- Ji Hee Hong
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- lung cancer
- liver cancer
- stomach cancer
- pancreas cancer
Exclusion Criteria:
- coagulopathy
- infection
- previous spine fusion at thoracic level
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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有源比较器：Active Comparator: supine position
Active Comparator: supine position thoracic epidural catheterization with supine position
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thoracic epidural catheterization thoracic epidural catheterization for the management of postoperative pain
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有源比较器：Active Comparator: flexed lateral position
Active Comparator: flexed lateral position thoracic epidural catheterization with flexed lateral position
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thoracic epidural catheterization thoracic epidural catheterization for the management of postoperative pain
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Epidural pressure
大体时间：15 minutes after the completion of the intervention
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Epidural pressure (mmHg) measurement using pressure transducer between different posture
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15 minutes after the completion of the intervention
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Contrast dye assessment
大体时间：5 minutes after the completion of the intervention
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Number of segment convered by contrast dye assessed through fluoroscopic image
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5 minutes after the completion of the intervention
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.
thoracic epidural catheterization的临床试验
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Cook Research Incorporated完全的
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Jesse Manunga, MDMinneapolis Heart Institute Foundation尚未招聘