The Effect of Exercise and/or Diet on Health Related Parameters
The Effect of Exercise and/or Diet Body Composition, Cardiorespiratory Fitness and Blood Parameters Related to Improved Health in Overweight Females.
研究概览
详细说明
Diet and exercise can both be efficient tools to reduce bodyweight, get healthier body composition and improve many different health related blood parameters such as cholesterol and glucose tolerance.
Exercise has superior effect on skeletal muscle in the context of glucose tolerance, but adherence to exercise program can be a huge challenge for overweight individuals. While exercise has profound effect on metabolic health, diet has been superior when it comes to weight reduction. Previous studies have shown that 5-7% weight loss can improve glucose tolerance, measured as reduced fasting glucose and reduced 2-hour post prandial glucose.
We wish to see if the combination exercise and diet is superior to diet only when it comes to over all health.
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
-
-
-
Oslo、挪威、0863
- Norwegian School of Sports Sciences
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Women
- Sedentary
- Premenopausal
- Caucasian
- BMI 26.9 - 36.1
- Age 33-4
- Living close to, or in Oslo.
Exclusion Criteria:
- Pregnancy
- Breast-feeding
- Smoking or tobacco use
- Previous medical history of cardio-vascular disease (CVD)
- Previous medical history of diabetes
- Previous medical history of endocrine disorder
- Previous medical history of kidney disease
- Use of lipid lowering medication
- Use of diabetes medication
学习计划
研究是如何设计的？
设计细节
- 主要用途：其他
- 分配：随机化
- 介入模型：阶乘赋值
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Normal diet
The group ingests normal diet, recommended by the health authorities
|
Normal diet recommended by the health authorities
|
|
实验性的：LCHF diet
The group ingests LCHF diet, a modified Atkins diet with 70 energy percentage fat
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LCHF Diet, a modified Atkins diet with high percentage of fat and very low percentage of karbohydrates
|
|
实验性的：Normal diet + exercise
The group ingests normal diet, recommended by the health authorities in addition to exercise program 3x week.
|
Normal diet recommended by the health authorities
Exercise program - indoor bicycle interval exercise, duration 60 min 3x week
|
|
实验性的：LCHF diet + exercise
The group ingests LCHF diet, a modified Atkins diet with 70 energy percentage fat, in addition to exercise program 3x week.
|
LCHF Diet, a modified Atkins diet with high percentage of fat and very low percentage of karbohydrates
Exercise program - indoor bicycle interval exercise, duration 60 min 3x week
|
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Area under curve (AUC) glucose
大体时间：Change from baseline AUC glucose at 10 weeks
|
AUC glucose measured during an OGTT
|
Change from baseline AUC glucose at 10 weeks
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Lipid profile
大体时间：Change from Baseline lipids at 10 weeks
|
Measurements of total cholesterol, LDL, HDL, TG
|
Change from Baseline lipids at 10 weeks
|
|
Body composition
大体时间：Change from baseline values at 10 weeks
|
Measurement of lean body mass, fat free mass, fat mass, visceral fat, bone mass
|
Change from baseline values at 10 weeks
|
|
Cardiorespiratory fitness
大体时间：Change from baseline values at 10 weeks
|
Measurement of peak oxygen uptake
|
Change from baseline values at 10 weeks
|
合作者和调查者
调查人员
- 首席研究员：Jørgen Jensen, Professor、Norwegian School of Sport Sciences, Section of Physical Performance
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
其他研究编号
- AMUC-NIH-LCHF-P3-2014
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
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