Portrayal of Hospital Alcohol Detoxification in France (Alcostop)
Portrayal of Hospital Alcohol Detoxifications and Factors Associated With Longer or Ulterior Hospitalizations in France From 2011 to 2020
研究概览
详细说明
Context:
In France, the consequences of excessive alcohol use are one of the primary reasons for hospitalization. When stopping the substance, patients with an alcohol use disorder can suffer from a potentially fatal alcohol withdrawal syndrome. To mitigate these risks, a withdrawal under medical supervision is possible, either in an outpatient setting or in hospital, where the detoxification can be programmed or imposed. In the course of an alcohol dependent patient's life, re-drinking is not exceptional and the patient may undergo several withdrawals during his or her life.
Psychiatric pathologies, especially anxiety and depression, are more frequent in these patients than in the rest of the population, just as can be somatic pathologies.e. Withdrawal accidents, represented by comital seizures and delirium tremens, can be critical.
In hospital detoxifications, studies do not show any benefit in continuing the stay beyond 10 days, except in the case of somatic or psychiatric complication. However, little information is available on the average length of stay for hospital alcohol detoxification.
Although alcohol dependence issues are very frequent and the resulting withdrawals are relatively common and associated with numerous comorbidities, little data exists at a national level in France.
The aim of this study is to describe these hospital detoxifications: course, duration, frequency and clinical and paraclinical characteristics of the patients. We also wish to analyze which characteristics are associated with longer stays or re-hospitalization and to compare the care according to the facility type.
Objectives:
Main:
- To describe the clinical, paraclinical, and stay characteristics of hospital alcohol detoxification in France
Secondary:
- To describe the regional distribution of hospital alcohol detoxification
- To evaluate whether certain clinical characteristics are associated with a longer hospital stays
- To evaluate whether certain clinical characteristics are associated with subsequent re-hospitalization for the same reason
- To compare the characteristics of patient stays by type of facility
Methods:
In this descriptive observational study using pre-existing data accessed via the PMSI (Programme de Médicalisation des Systèmes d'Information), we will use all hospital stays from 2011 to 2020 for alcohol detoxification in France, both in public and private settings.
For each hospital stay will be collected the length, the antecedents of hospital alcohol detoxification, clinical and psychiatric comorbidities, withdrawals complication, alcohol use complication, further examinations.
We will describe the stays using median and quartiles for continuous variables and number and percentage for dichotomous variables. For secondary objectives, we will use a multivariate linear regression model if the length of stay is normal, an ordinal regression model otherwise. The characteristics of the stays will be compared regarding the type of facility using univariate comparative tests: Chi² or Fisher for dichotomous variables and Student or Mann-Whitney for continuous variables.
研究类型
注册 (实际的)
联系人和位置
学习地点
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-
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Montpellier、法国、34295
- Uhmontpellier
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-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion criteria:
Inclusion criteria:
- French patients of at least 18 years old
- Inpatients of a public or private care facility for alcohol detoxification
- From 01/01/2011 to 12/31/2020
- In a medical or psychiatric hospital
Exclusion criteria:
- age < 18 years
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
干预/治疗 |
---|---|
Inpatients for alcohol detoxifications
French patients who were hospitalized for alcohol detoxification from 2011 to 2020
|
Stay for alcohol detoxification : routine care.
|
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
description of age
大体时间:day 1 (At hospital inclusion)
|
Age at admission (in years), calculated by the difference of the year of admission and the year of birth through the PMSI.
|
day 1 (At hospital inclusion)
|
description of sex
大体时间:day 1 (At hospital inclusion)
|
Sex collected through the PMSI.
|
day 1 (At hospital inclusion)
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
description of geographic code
大体时间:day 1 (At hospital inclusion)
|
Sex collected through the PMSI.
|
day 1 (At hospital inclusion)
|
description of CMU-C
大体时间:day 1 (At hospital inclusion)
|
CMU-C (universal complementary health insurance, collected through the PMSI.
|
day 1 (At hospital inclusion)
|
Length of stay
大体时间:During the stay (day 1 - day 15)
|
Length of stay (in days), calculated by the difference between the discharge date and the entry date, collected through the PMSI.
|
During the stay (day 1 - day 15)
|
Care establishment
大体时间:During the stay (day 1 - day 15)
|
Name and type of the care establishment, collected through the PMSI.
|
During the stay (day 1 - day 15)
|
Number of previous hospital detoxification stays in the studied period
大体时间:During the stay (day 1 - day 15)
|
Number of previous hospital detoxification stays in the studied period, collected through the PMSI.
|
During the stay (day 1 - day 15)
|
Psychiatric comorbidities
大体时间:During the stay (day 1 - day 15)
|
Psychiatric comorbidities (Major depression episode, anxiety, psychotic trouble, personality diseases), collected through the PMSI.
|
During the stay (day 1 - day 15)
|
Withdrawal complication
大体时间:During the stay (day 1 - day 15)
|
Withdrawal complications (delirium tremens, comitial seizures), collected through the PMSI.
|
During the stay (day 1 - day 15)
|
Further examination
大体时间:During the stay (day 1 - day 15)
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Further examination (biology, imagery, etc…), collected through the PMSI.
|
During the stay (day 1 - day 15)
|
Re-hospitalization for same reason
大体时间:day 1
|
For each patient, and each stay, we will evaluate if the patient had an ulterior re-hospitalization for alcohol withdrawal.
Collected through the PMSI.
|
day 1
|
合作者和调查者
调查人员
- 首席研究员:Lionel MOULIS、University Hospital, Montpellier
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
关键字
其他研究编号
- RECHMPL21_0456
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)?
IPD 计划说明
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