Influence of Square-stepping Exercise on Brain Activation, Cognitive Function and Physical Performance in Frail Elders With MCI
研究概览
详细说明
Background:
Both frailty and MCI exert negative impact on motor and cognitive function, which increase the risks of fall and adverse health condition. SSE has been proved to be an effective intervention for motor and cognitive function in older adults. However, the underlying mechanisms of SSE still remain undetermined for its possible effects. This study aims to elucidate the possible mechanisms of SSE in frail elders with MCI.
Methods:
This is a cross-sectional study. The inclusion criteria are: (1) age between 65 and 90 years old, (2) the presence of at least 1 characteristic of the Fried frailty criteria, (3) with mini-mental state examination (MMSE) score≧24 and Montreal Cognitive Assessment (MoCA) score <26 (MCI criteria), and (4) ability to walk independently for 1 min without assistive devices. The exclusion criteria are: (1) central nervous system disorders (such as stroke, Parkinson's disease, spinal cord injury), and (2) any unstable physical condition, psychiatric disorder, and other neurological disorder or diagnosed with learning disability which may affect participating this study. Brain activity during SSE and usual walking, SSE performance, physical performance, and cognitive function are measured. The purpose of this study is to elucidate the possible mechanisms of SSE by examining brain activation differences between SSE patterns and usual walking, as well as the relationship between brain activity and SSE performance, between cognitive function and SSE performance, and between physical performance and SSE performance in frail elders with MCI.
研究类型
注册 (预期的)
联系人和位置
学习联系方式
- 姓名:Ray-Yau Wang, PhD
- 电话号码:+886-2-28267210
- 邮箱:rywang@nycu.edu.tw
学习地点
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Taipei、台湾、112
- 招聘中
- National Yang Ming Chiao Tung University
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接触:
- Ray-Yau Wang, PhD
- 电话号码:+886-2-28267210
- 邮箱:rywang@nycu.edu.tw
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Age between 65 and 90 years old
- Presence of at least 1 characteristic of the Fried frailty criteria
- Mini-mental state examination score equal to or more than 24
- Montreal Cognitive Assessment score less than 26
- Ability to walk independently for 1 min without assistive devices
Exclusion Criteria:
- Central nervous system disorders (such as stroke, Parkinson's disease, spinal cord injury)
- Any unstable physical condition, psychiatric disorder, and other neurological disorder or diagnosed with learning disability which may affect participating this study
学习计划
研究是如何设计的?
设计细节
- 观测模型:其他
- 时间观点:横截面
队列和干预
团体/队列 |
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Older adults with frailty and mild cognitive impairment
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Brain activity
大体时间:20 minutes
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The brain activity will be measured under 3 tasks: usual walking, SSE-pattern1 (SSE1), and SSE-pattern 2 (SSE2)
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20 minutes
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SSE performance
大体时间:15 minutes
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The number of the correct steps that participants complete in 1 min during SSEs will be recorded
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15 minutes
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Montreal Cognitive Assessment
大体时间:15 minutes
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Global cognitive function
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15 minutes
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Trail making test
大体时间:5 minutes
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Executive function
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5 minutes
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Stroop color and word test
大体时间:5 minutes
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Executive function
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5 minutes
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Digit span test
大体时间:8 minutes
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Executive function
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8 minutes
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Timed up and go test
大体时间:5 minutes
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Dynamic balance and functional mobility
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5 minutes
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Berg balance scale
大体时间:15 minutes
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Balance and fall risk
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15 minutes
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Five times sit to stand test
大体时间:3 minutes
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Lower extremity strength
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3 minutes
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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