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BEAT-SHOCK Registry (BEAT-SHOCK)

2026年6月8日更新者：University Hospital, Basel, Switzerland

BEAT-SHOCK (Basel Evaluation of Acute Therapy in Cardiogenic SHOCK) Registry

This regulation defines the purpose, the operational processes, and the organization of the registry BEAT-SHOCK (Basel Evaluation of Acute Therapy in cardiogenic SHOCK). It describes the requirements for collecting, storing, processing, managing and sharing health-related registry data.

研究概览

地位

招聘中

条件

干预/治疗

其他：no internvention

研究类型

观察性的

注册 (估计的)

8000

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习联系方式

姓名：Jasper Boeddinghaus, PD Dr. med.
电话号码：0041613287897
邮箱：jasper.boeddinghaus@usb.ch

研究联系人备份

姓名：Gregor Leibundgut, Prof. Dr.
电话号码：0041613287897
邮箱：gregor.leibundgut@usb.ch

学习地点

瑞士
- Canton of Basel-City
  - Basel、Canton of Basel-City、瑞士、4031
    - 招聘中
    - University Hospital Basel
    - 首席研究员：
      
      Jasper Boeddinghaus, PD Dr. med.
    - 接触：
      
      Jasper Boeddinghaus, PD Dr. med.
      
      电话号码：0041613287897
      
      邮箱：jasper.boeddinghaus@usb.ch
    - 接触：
      
      Gregor Leibundgut, Prof. Dr. med.
      
      邮箱：gregor.leibundgut@usb.ch
    - 首席研究员：
      
      Gregor Leibundgut, Prof. Dr. med.

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

成人
年长者

接受健康志愿者

不

取样方法

非概率样本

研究人群

Adult patients who are treated at the University Hospital Basel and are diagnosed with cardiogenic shock, irrespective of underlying etiology or therapeutic strategy. The registry includes a wide range of cardiogenic shock etiologies, including:

Myocardial infarction (MI)
Fulminant myocarditis
Acute decompensated heart failure
Severe valvular disease
Post-cardiotomy or perioperative cardiogenic shock

描述

Patients admitted with cardiogenic shock to the University hospital Basel (diagnosis at the time of admission) or development of cardiogenic shock during the hospital stay
Age ≥18 years
Provision of written ICF
Clinical diagnosis of cardiogenic shock.
impaired organ perfusion due to primary cardiac dysfunction,
persistent systolic blood pressure (SBP) <90 mmHg for ≥30 minutes, or the need for vasopressors, inotropes, or mechanical circulatory support (MCS) to maintain adequate perfusion and
evidence of systemic hypoperfusion with arterial lactate ≥2 mmol/L or venous lactate ≥3 mmol/l and ≥1 of the following:
Cold or clammy extremities
Altered mental status
Reduced urine output
Signs of volume overload or congestion (on clinical exam, imaging, or invasive monitoring)
Patients with normotensive cardiogenic shock (SBP ≥90 mmHg without vasopressors or MCS) may also be included if clear signs of hypoperfusion (arterial lactate ≥2 mmol/L or venous lactate ≥3 mmol/l) and cardiac dysfunction are present and alternative causes are excluded

Exclusion criteria:

Age <18 years
Refusal to provide informed consent by the patient or their legally authorized representative

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

研究衡量的是什么？

主要结果指标

结果测量	措施说明	大体时间
In-Hospital all-cause mortality occurring before discharge from the participating study centre 大体时间：10 years	In-hospital all-cause mortality is defined as death occurring before discharge from the participating study centre. Deaths occurring after transfer to an external hospital are not counted as in-hospital deaths, but are captured through follow-up for 30-day and 90-day mortality.	10 years

次要结果测量

结果测量	措施说明	大体时间
30-day and 90-day all-cause Mortality 大体时间：30, 90 days	30-day and 90-day all-cause mortality occuring after discharge from the participating study centre.	30, 90 days
Need for organ support at any time during hospitalization 大体时间：30, 60, 360 days	The need for organ support at any time during hospitalization (including renal replacement therapy, mechanical circulation support irrespective of type, and vasoactive or inotropic therapy)	30, 60, 360 days
Acute kidney injury (AKI) within 36 hours after index diagnosis of cardiogenic shock/index presentation 大体时间：Within 36 hours after index diagnosis of cardiogenic shock/ index presentation.	Occurence of AKI (defined as an increase in serum creatinine of at least 26 µmol/L (0.3 mg/dL)	Within 36 hours after index diagnosis of cardiogenic shock/ index presentation.

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

University Hospital, Basel, Switzerland

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2025年10月1日

初级完成 (估计的)

2035年10月1日

研究完成 (估计的)

2035年10月1日

研究注册日期

首次提交

2026年5月29日

首先提交符合 QC 标准的

2026年6月8日

首次发布 (实际的)

2026年6月11日

研究记录更新

最后更新发布 (实际的)