Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Relationship Between Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration. Neuromuscular impairments associated with MS, including muscle weakness, spasticity, fatigue, and proprioceptive deficits, may lead to alterations in spinal posture and reduced spinal mobility. These changes can negatively affect trunk control, balance, respiratory function, and functional independence.
Although postural abnormalities and mobility limitations have been reported in individuals with MS, the relationship between spinal posture, spinal mobility, and balance remains insufficiently investigated. Therefore, this study aims to examine the associations between spinal posture, spinal mobility, and balance performance in individuals with multiple sclerosis. Improved understanding of these relationships may contribute to the development of targeted rehabilitation interventions aimed at enhancing postural control and functional outcomes in this population. This study further hypothesises that alterations in spinal posture and spinal mobility are associated with impaired balance performance in individuals with multiple sclerosis.
研究概览
研究类型
注册 (估计的)
联系人和位置
学习地点
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Çubuk
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Ankara、Çubuk、土耳其(türkiye)、06760
- 招聘中
- Ankara Yıldırım Beyazıt University
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接触:
- Yasemin Ateş Sarı
- 电话号码:05397799535
- 邮箱:yaseminates48@gmail.com
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
- Diagnosis of relapsing-remitting multiple sclerosis (RRMS)
- Aged between 18 and 65 years
- EDSS score between 0.5 and 4.5
- Standardized Mini-Mental State Examination score ≥24
Exclusion Criteria:
- Receipt of corticosteroid treatment within the previous 4 weeks
- Presence of any additional neurological disorder
- Spasticity defined as a Modified Ashworth Scale score ≥3
- History of surgical intervention involving the lower extremities, spine, or abdominal region
学习计划
研究是如何设计的?
设计细节
队列和干预
团体/队列 |
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多发性硬化症
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
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Spinal alignment
大体时间:1 hour
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Spinal alignment was assessed in the sagittal and frontal planes during neutral standing, maximal trunk flexion, and maximal trunk extension.
All spinal alignment parameters were recorded as angular values and expressed in degrees (°).
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1 hour
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Spinal mobility
大体时间:1 hour
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Spinal mobility was assessed in both the sagittal and frontal planes.
In the sagittal plane, mobility was calculated as the angular difference between the neutral standing posture and maximal trunk flexion and extension positions.
In the frontal plane, lateral flexion mobility was calculated as the angular difference between the neutral standing posture and maximal right and left lateral flexion positions.
All measurements were recorded in degrees (°).
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1 hour
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
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Single-Leg Stance
大体时间:1 hour
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Single-leg stance time was recorded in seconds, with shorter durations indicating poorer balance performance.
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1 hour
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Time Up and Go
大体时间:1 hour
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Dynamic balance was assessed using the Timed Up and Go test.
Performance was recorded as the time required to complete the task (seconds), with longer times indicating poorer dynamic balance.
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1 hour
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- 08/1456
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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