Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Relationship Between Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration. Neuromuscular impairments associated with MS, including muscle weakness, spasticity, fatigue, and proprioceptive deficits, may lead to alterations in spinal posture and reduced spinal mobility. These changes can negatively affect trunk control, balance, respiratory function, and functional independence.
Although postural abnormalities and mobility limitations have been reported in individuals with MS, the relationship between spinal posture, spinal mobility, and balance remains insufficiently investigated. Therefore, this study aims to examine the associations between spinal posture, spinal mobility, and balance performance in individuals with multiple sclerosis. Improved understanding of these relationships may contribute to the development of targeted rehabilitation interventions aimed at enhancing postural control and functional outcomes in this population. This study further hypothesises that alterations in spinal posture and spinal mobility are associated with impaired balance performance in individuals with multiple sclerosis.
Aperçu de l'étude
Statut
Les conditions
Type d'étude
Inscription (Estimé)
Contacts et emplacements
Lieux d'étude
-
-
Çubuk
-
Ankara, Çubuk, Turquie (Türkiye), 06760
- Recrutement
- Ankara Yıldırım Beyazıt University
-
Contact:
- Yasemin Ateş Sarı
- Numéro de téléphone: 05397799535
- E-mail: yaseminates48@gmail.com
-
-
Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
- Adulte
- Adulte plus âgé
Accepte les volontaires sains
Méthode d'échantillonnage
Population étudiée
La description
Inclusion Criteria:
- Diagnosis of relapsing-remitting multiple sclerosis (RRMS)
- Aged between 18 and 65 years
- EDSS score between 0.5 and 4.5
- Standardized Mini-Mental State Examination score ≥24
Exclusion Criteria:
- Receipt of corticosteroid treatment within the previous 4 weeks
- Presence of any additional neurological disorder
- Spasticity defined as a Modified Ashworth Scale score ≥3
- History of surgical intervention involving the lower extremities, spine, or abdominal region
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
Cohortes et interventions
Groupe / Cohorte |
|---|
|
Sclérose en plaques
|
Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Spinal alignment
Délai: 1 hour
|
Spinal alignment was assessed in the sagittal and frontal planes during neutral standing, maximal trunk flexion, and maximal trunk extension.
All spinal alignment parameters were recorded as angular values and expressed in degrees (°).
|
1 hour
|
|
Spinal mobility
Délai: 1 hour
|
Spinal mobility was assessed in both the sagittal and frontal planes.
In the sagittal plane, mobility was calculated as the angular difference between the neutral standing posture and maximal trunk flexion and extension positions.
In the frontal plane, lateral flexion mobility was calculated as the angular difference between the neutral standing posture and maximal right and left lateral flexion positions.
All measurements were recorded in degrees (°).
|
1 hour
|
Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
|---|---|---|
|
Single-Leg Stance
Délai: 1 hour
|
Single-leg stance time was recorded in seconds, with shorter durations indicating poorer balance performance.
|
1 hour
|
|
Time Up and Go
Délai: 1 hour
|
Dynamic balance was assessed using the Timed Up and Go test.
Performance was recorded as the time required to complete the task (seconds), with longer times indicating poorer dynamic balance.
|
1 hour
|
Collaborateurs et enquêteurs
Parrainer
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude (Réel)
Achèvement primaire (Estimé)
Achèvement de l'étude (Estimé)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Réel)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Réel)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- 08/1456
Informations sur les médicaments et les dispositifs, documents d'étude
Étudie un produit pharmaceutique réglementé par la FDA américaine
Étudie un produit d'appareil réglementé par la FDA américaine
Ces informations ont été extraites directement du site Web clinicaltrials.gov sans aucune modification. Si vous avez des demandes de modification, de suppression ou de mise à jour des détails de votre étude, veuillez contacter register@clinicaltrials.gov. Dès qu'un changement est mis en œuvre sur clinicaltrials.gov, il sera également mis à jour automatiquement sur notre site Web .