Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Relationship Between Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration. Neuromuscular impairments associated with MS, including muscle weakness, spasticity, fatigue, and proprioceptive deficits, may lead to alterations in spinal posture and reduced spinal mobility. These changes can negatively affect trunk control, balance, respiratory function, and functional independence.
Although postural abnormalities and mobility limitations have been reported in individuals with MS, the relationship between spinal posture, spinal mobility, and balance remains insufficiently investigated. Therefore, this study aims to examine the associations between spinal posture, spinal mobility, and balance performance in individuals with multiple sclerosis. Improved understanding of these relationships may contribute to the development of targeted rehabilitation interventions aimed at enhancing postural control and functional outcomes in this population. This study further hypothesises that alterations in spinal posture and spinal mobility are associated with impaired balance performance in individuals with multiple sclerosis.
Studieoversikt
Status
Forhold
Studietype
Registrering (Antatt)
Kontakter og plasseringer
Studiesteder
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Çubuk
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Ankara, Çubuk, Tyrkia (Türkiye), 06760
- Rekruttering
- Ankara Yıldırım Beyazıt University
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Ta kontakt med:
- Yasemin Ateş Sarı
- Telefonnummer: 05397799535
- E-post: yaseminates48@gmail.com
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Deltakelseskriterier
Kvalifikasjonskriterier
Alder som er kvalifisert for studier
- Voksen
- Eldre voksen
Tar imot friske frivillige
Prøvetakingsmetode
Studiepopulasjon
Beskrivelse
Inclusion Criteria:
- Diagnosis of relapsing-remitting multiple sclerosis (RRMS)
- Aged between 18 and 65 years
- EDSS score between 0.5 and 4.5
- Standardized Mini-Mental State Examination score ≥24
Exclusion Criteria:
- Receipt of corticosteroid treatment within the previous 4 weeks
- Presence of any additional neurological disorder
- Spasticity defined as a Modified Ashworth Scale score ≥3
- History of surgical intervention involving the lower extremities, spine, or abdominal region
Studieplan
Hvordan er studiet utformet?
Designdetaljer
Kohorter og intervensjoner
Gruppe / Kohort |
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Multippel sklerose
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Hva måler studien?
Primære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
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Spinal alignment
Tidsramme: 1 hour
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Spinal alignment was assessed in the sagittal and frontal planes during neutral standing, maximal trunk flexion, and maximal trunk extension.
All spinal alignment parameters were recorded as angular values and expressed in degrees (°).
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1 hour
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Spinal mobility
Tidsramme: 1 hour
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Spinal mobility was assessed in both the sagittal and frontal planes.
In the sagittal plane, mobility was calculated as the angular difference between the neutral standing posture and maximal trunk flexion and extension positions.
In the frontal plane, lateral flexion mobility was calculated as the angular difference between the neutral standing posture and maximal right and left lateral flexion positions.
All measurements were recorded in degrees (°).
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1 hour
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Sekundære resultatmål
Resultatmål |
Tiltaksbeskrivelse |
Tidsramme |
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Single-Leg Stance
Tidsramme: 1 hour
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Single-leg stance time was recorded in seconds, with shorter durations indicating poorer balance performance.
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1 hour
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Time Up and Go
Tidsramme: 1 hour
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Dynamic balance was assessed using the Timed Up and Go test.
Performance was recorded as the time required to complete the task (seconds), with longer times indicating poorer dynamic balance.
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1 hour
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Samarbeidspartnere og etterforskere
Studierekorddatoer
Studer hoveddatoer
Studiestart (Faktiske)
Primær fullføring (Antatt)
Studiet fullført (Antatt)
Datoer for studieregistrering
Først innsendt
Først innsendt som oppfylte QC-kriteriene
Først lagt ut (Faktiske)
Oppdateringer av studieposter
Sist oppdatering lagt ut (Faktiske)
Siste oppdatering sendt inn som oppfylte QC-kriteriene
Sist bekreftet
Mer informasjon
Begreper knyttet til denne studien
Ytterligere relevante MeSH-vilkår
Andre studie-ID-numre
- 08/1456
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