Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Relationship Between Spinal Alignment, Spinal Mobility, and Balance in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelination and axonal degeneration. Neuromuscular impairments associated with MS, including muscle weakness, spasticity, fatigue, and proprioceptive deficits, may lead to alterations in spinal posture and reduced spinal mobility. These changes can negatively affect trunk control, balance, respiratory function, and functional independence.
Although postural abnormalities and mobility limitations have been reported in individuals with MS, the relationship between spinal posture, spinal mobility, and balance remains insufficiently investigated. Therefore, this study aims to examine the associations between spinal posture, spinal mobility, and balance performance in individuals with multiple sclerosis. Improved understanding of these relationships may contribute to the development of targeted rehabilitation interventions aimed at enhancing postural control and functional outcomes in this population. This study further hypothesises that alterations in spinal posture and spinal mobility are associated with impaired balance performance in individuals with multiple sclerosis.
Studieoversigt
Status
Betingelser
Undersøgelsestype
Tilmelding (Anslået)
Kontakter og lokationer
Studiesteder
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Çubuk
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Ankara, Çubuk, Tyrkiet (Türkiye), 06760
- Rekruttering
- Ankara Yıldırım Beyazıt University
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Kontakt:
- Yasemin Ateş Sarı
- Telefonnummer: 05397799535
- E-mail: yaseminates48@gmail.com
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
- Voksen
- Ældre voksen
Tager imod sunde frivillige
Prøveudtagningsmetode
Studiebefolkning
Beskrivelse
Inclusion Criteria:
- Diagnosis of relapsing-remitting multiple sclerosis (RRMS)
- Aged between 18 and 65 years
- EDSS score between 0.5 and 4.5
- Standardized Mini-Mental State Examination score ≥24
Exclusion Criteria:
- Receipt of corticosteroid treatment within the previous 4 weeks
- Presence of any additional neurological disorder
- Spasticity defined as a Modified Ashworth Scale score ≥3
- History of surgical intervention involving the lower extremities, spine, or abdominal region
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
Kohorter og interventioner
Gruppe / kohorte |
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Multipel sclerose
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Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Spinal alignment
Tidsramme: 1 hour
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Spinal alignment was assessed in the sagittal and frontal planes during neutral standing, maximal trunk flexion, and maximal trunk extension.
All spinal alignment parameters were recorded as angular values and expressed in degrees (°).
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1 hour
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Spinal mobility
Tidsramme: 1 hour
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Spinal mobility was assessed in both the sagittal and frontal planes.
In the sagittal plane, mobility was calculated as the angular difference between the neutral standing posture and maximal trunk flexion and extension positions.
In the frontal plane, lateral flexion mobility was calculated as the angular difference between the neutral standing posture and maximal right and left lateral flexion positions.
All measurements were recorded in degrees (°).
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1 hour
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Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
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Single-Leg Stance
Tidsramme: 1 hour
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Single-leg stance time was recorded in seconds, with shorter durations indicating poorer balance performance.
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1 hour
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Time Up and Go
Tidsramme: 1 hour
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Dynamic balance was assessed using the Timed Up and Go test.
Performance was recorded as the time required to complete the task (seconds), with longer times indicating poorer dynamic balance.
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1 hour
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Samarbejdspartnere og efterforskere
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Anslået)
Studieafslutning (Anslået)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Faktiske)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- 08/1456
Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter
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Kliniske forsøg med Multipel sclerose
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Baskent UniversityIkke rekrutterer endnuMULTIPL SKLEROSETyrkiet (Türkiye)
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