This Prospective Observational Study Aims to Evaluate the Capability of Ultra-high-resolution Photon-counting CT Angiography (UHR PCD-CTA) for Noninvasive Evaluation of Intracranial Venous Sinus Stents. The Study Will Compare Image Quality, Stent Visualization, Metal-related Artifacts, and Diagnosti
Evaluation of Ultra-High-Resolution Photon-Counting CT Angiography for Intracranial Venous Sinus Stent Assessment
研究概览
地位
详细说明
Intracranial venous sinus stenting has become an important treatment option for patients with symptomatic venous sinus stenosis, particularly those with idiopathic intracranial hypertension. Accurate imaging follow-up after stent placement is essential for evaluating stent patency, recurrent stenosis, and potential complications such as in-stent thrombosis or occlusion.
Conventional CT angiography (CTA) is commonly used for noninvasive follow-up after venous sinus stent implantation; however, accurate assessment of stented venous sinuses remains challenging due to metal-related artifacts. Blooming artifact caused by the high attenuation of metallic stent material may result in overestimation of stent thickness and obscuration of the stent lumen. In addition, beam-hardening artifacts from the stent and adjacent skull structures may further degrade image quality and reduce diagnostic confidence, potentially limiting the ability of CTA to detect clinically significant restenosis or thrombotic complications.
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名：Jinhao Lyu, MD
- 电话号码：+8615903562929
- 邮箱：330322990@qq.com
研究联系人备份
- 姓名：Jinying He
- 邮箱：1527012389@qq.com
学习地点
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Beijing Municipality
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Beijing、Beijing Municipality、中国、100853
- 招聘中
- Chinese PLA General Hospital
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接触：
- Jinhao Lyu, MD
- 电话号码：+8615903562929
- 邮箱：330322990@qq.com
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接触：
- Jinying He
- 电话号码：+8613854153820
- 邮箱：1527012389@qq.com
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-
参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
- Adults aged ≥18 years.
- History of intracranial venous sinus stent implantation.
- Undergoing follow-up contrast-enhanced CT angiography after stent -placement.
- Available clinical and imaging data.
Exclusion Criteria:
- Severe motion artifacts affecting image interpretation.
- Contraindication to iodinated contrast media.
- Severe renal impairment preventing contrast-enhanced CT examination.
- Incomplete imaging data.
- Other conditions preventing reliable assessment of the venous sinus stent.
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
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Patients With Intracranial Venous Sinus Stenosis
Patients with symptomatic intracranial venous sinus stenosis who underwent CT angiography before and after venous sinus stent implantation.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Agreement between UHR PCD-CTA and DSA for intracranial venous sinus stent patency
大体时间：1-4 years
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Agreement between ultra-high-resolution photon-counting detector CT angiography (UHR PCD-CTA) and digital subtraction angiography (DSA) for the assessment of intracranial venous sinus stent patency will be quantified using Cohen's kappa (κ) coefficient.
Stent patency will be classified according to the predefined diagnostic criteria, with DSA serving as the reference standard.
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1-4 years
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Signal-to-noise ratio on UHR PCD-CTA
大体时间：1-4years
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Signal-to-noise ratio (SNR) will be calculated using CT attenuation and image noise measurements obtained from predefined regions of interest on UHR PCD-CTA images.
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1-4years
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合作者和调查者
赞助
调查人员
- 学习椅：Xin Lou、Chinese PLA General Hospital
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- PCD-CT venous Stent
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研究美国 FDA 监管的设备产品
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