此页面是自动翻译的，不保证翻译的准确性。请参阅 英文版 对于源文本。

Peroxide Versus Non-Peroxide In-Office Tooth Bleaching: A Randomized Clinical Trial (BECTS)

2026年9月8日 更新者：Esraa Eid Qurany、Minia University

Bleaching Efficacy, Color Durability, and Tooth Sensitivity After In-Office Bleaching With Peroxide Versus Non-Peroxide Systems: A Randomized Clinical Trial

This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems. The study will evaluate tooth whitening efficacy, color durability over time, and tooth sensitivity after treatment. Participants will receive one of the two bleaching treatments and will be followed for six months to assess the clinical outcomes and compare the performance of both systems.

研究概览

地位

招聘中

条件

干预/治疗

详细说明

This randomized controlled clinical trial is designed to compare the clinical performance of peroxide-based and non-peroxide in-office tooth bleaching systems. Eligible participants will be randomly allocated into two treatment groups. Tooth color will be assessed using standardized clinical evaluation methods before treatment, immediately after bleaching, and during follow-up visits. The study will also evaluate color stability and tooth sensitivity over a six-month follow-up period. The findings are expected to provide evidence regarding the effectiveness and safety of both bleaching systems and to support evidence-based clinical decision-making in esthetic dentistry.

研究类型

介入性

注册 (估计的)

50

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习联系方式

学习地点

  • 埃及
    • Minya Governorate
      • Minya、Minya Governorate、埃及
        • 招聘中
        • Minia University Hospital
        • 接触：

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

是的

描述

Inclusion Criteria:

  • Adults aged 18-45 years.
  • Good general health.
  • Presence of all maxillary anterior teeth free from restorations, caries, or structural defects.
  • Baseline tooth shade suitable for bleaching assessment.
  • Good oral hygiene and periodontal health.
  • Willingness to comply with the study protocol and attend all follow-up visits.
  • Signed informed consent.

Exclusion Criteria:

  • Pregnancy or lactation.
  • History of tooth hypersensitivity.
  • Active caries or defective restorations in the anterior teeth.
  • Intrinsic tooth discoloration (e.g., fluorosis, tetracycline staining).
  • Ongoing orthodontic treatment.
  • Smoking.
  • Use of tooth-whitening products within the previous 6 months.
  • Allergy to any component of the bleaching materials.

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 主要用途：治疗
  • 分配：随机化
  • 介入模型：并行分配
  • 屏蔽：单身的

武器和干预

参与者组/臂
干预/治疗
实验性的：Peroxide-based in office bleaching
Participants will receive a peroxide-based in-office tooth bleaching treatment according to the manufacturer's instructions.
程序：peroxide -based in office tooth bleaching
Participants will receive an in-office peroxide-based tooth bleaching treatment using the bleaching system according to the manufacturer's instructions.
实验性的：Non-peroxide-based in office bleaching
Participants will receive a non-peroxide-based in-office tooth bleaching treatment according to the manufacturer's instructions.
程序：non-peroxide -based in office tooth bleaching
Participants will receive an in-office non- peroxide-based tooth bleaching treatment using the bleaching system according to the manufacturer's instructions.

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Bleaching efficacy measured by Whiteness Index for Dentistry (WID)
大体时间：Baseline, immediately after treatment, 1 month, 3 months, and 6 months after treatment
Bleaching efficacy will be assessed using the Whiteness Index for Dentistry (WID) obtained by spectrophotometric measurements of the anterior teeth.
Baseline, immediately after treatment, 1 month, 3 months, and 6 months after treatment
Color durability measured by CIEDE2000 color difference (ΔE00)
大体时间：Baseline, immediately after treatment, 1 month, 3 months, and 6 months after treatment
Color durability will be evaluated using spectrophotometric color measurements and expressed as CIEDE2000 color difference (ΔE00).
Baseline, immediately after treatment, 1 month, 3 months, and 6 months after treatment
Tooth sensitivity assessed using the Visual Analog Scale (VAS)
大体时间：Daily during the 14-day treatment period
ooth sensitivity will be evaluated using a 0-10 Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates the worst possible pain
Daily during the 14-day treatment period

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

Minia University

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (估计的)

2026年8月15日

初级完成 (估计的)

2027年2月15日

研究完成 (估计的)

2027年3月15日

研究注册日期

首次提交

2026年9月8日

首先提交符合 QC 标准的

2026年9月8日

首次发布 (实际的)

2026年9月14日

研究记录更新

最后更新发布 (实际的)

2026年9月14日

上次提交的符合 QC 标准的更新

2026年9月8日

最后验证

2026年9月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • MU-1301-2026
  • 1301/2026 (其他标识符：Research Ethics Committee, Faculty of Dentistry, Minia University)

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)？

不

IPD 计划说明

individual participant data will not be shared because there is no plan for public data sharing beyond the analyses and results reported in the study.

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

订阅