- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00275886
Activation and Recruitment of GIL During Hp Infection
Activation and Recruitment of Gastric Infiltrating Lymphocytes During H. Pylori Infection
Study Overview
Status
Conditions
Detailed Description
Specific Aim #1: Characterization of the gastric infiltrating T cells from H. pylori gastritis patients A. Patients H. pylori infected gastritis and asymptomatic patients are selected from National Taiwan University hospital. The gastric biopsy specimen are taken from endoscopic biopsy in routine health check up or panendoscopic examination for the despeptic patients. HP negative gastritis patients will also be studied for negative control.
B. Immunohistochemical identification of T cells and expression of chemokine receptors.
Specific Aim #2 . Isolation and characterization of chemokines and chemokine receptors of the infiltrating lymphocytes in H. pylori-associated gastritis tissue
A. Isolation of gastric infiltrating lymphocyte B. Identification of the expression of chemokine receptor in gastric infiltrating lymphocytes by flow cytometry C. Detection of expression of chemokines in gastric tissues
Study Type
Enrollment
Contacts and Locations
Study Contact
- Name: Ping-Ning Hsu, MD, PhD
- Phone Number: 8635 886-2-23123456
- Email: phsu@ha.mc.ntu.edu.tw
Study Locations
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Taipei, Taiwan
- Recruiting
- National Taiwan University Hospital
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Contact:
- Ping-Ning Hsu, MD, PhD
- Phone Number: 8635 +886-223123456
- Email: phsu@ha.mc.ntu.edu.tw
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Principal Investigator:
- Ping-Ning Hsu, MD, PhD
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- patients receiveing endoscopy examination due to dyspepsia
Exclusion Criteria:
- nil
Study Plan
How is the study designed?
Design Details
- Observational Models: Case-Control
- Time Perspectives: Other
Collaborators and Investigators
Investigators
- Principal Investigator: Ping-Ning Hsu, MD, PhD, Department of Immunology
Study record dates
Study Major Dates
Study Start
Study Completion
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 9461701221
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