- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00371969
Reducing Unsafe Alcohol Use in HIV-Positive Individuals
Reducing Unsafe Drinking in HIV Primary Care
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
HIV infection is a widespread health problem in the U.S. Antiretroviral treatment has increased longevity and changed the nature of risk factors for morbidity and mortality. Alcohol consumption has become an increasingly serious health issue among HIV primary care patients. Drinking is a key factor in progression to severe liver damage (especially those co-infected with hepatitis), and liver disease is now one of the most common causes of death among those with HIV. Excess drinking is also associated with medication noncompliance, reduces the effect of antiretroviral treatment, and is linked to other health problems. Therefore, helping HIV patients reduce unsafe drinking is crucial to their long-term health. The intervention combines the brief MI, an established, evidence-based counseling approach, with an innovative procedure designed to strengthen the effects of the MI. An effective, easily implemented alcohol-reduction intervention could be incorporated into standard care in HIV clinics helping prevent or slow the progress of some medical problems in HIV-infected individuals, improve medication compliance, prolong lifespan and decrease risk behavior associated with alcohol use.
Comparison(s): Enhanced brief motivational interview (including an IVR component for alcohol self-monitoring purposes), brief motivational interview, viewing a DVD on HIV self-care.
Study Type
Enrollment (Actual)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
New York
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New York, New York, United States, 10032
- New York State Psychiatric Institute/ St. Vincent's Hospital
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-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Male and females 18 years of age or older.
- Participants have had 4 or more drinks on any day in the prior 30 days assessed via standardized questions.
- Participants are referred to a study MI counselor by clinic staff as needing an intervention for drinking
- Participants agree to random assignment and provide informed consent
Exclusion Criteria:
- Participants who are currently psychotic, suicidal or homicidal.
- Participants who have definite plans to leave the greater New York metropolitan area within the study period.
- Participants who demonstrate gross cognitive impairment as evidenced on the Halstead-Reitain Trails (A).
- Participants who do not speak English or Spanish, or have hearing impairments that preclude use of the telephone.
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: 1 - enhanced MI
Enhanced brief motivational interview (including an IVR component for alcohol self-monitoring purposes)
|
The intervention consists of a brief motivational interview, which is combined with daily alcohol monitoring through the use of an interactive voice response system IVR (automated telephone system).
|
Active Comparator: 2- standard MI
The intervention consists of a standard motivational interview or viewing a DVD on HIV self-care.
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Brief motivational interview, viewing a DVD on HIV self-care.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Alcohol consumption in the last 30 days, assessed at baseline and repeatedly during follow-up so that change can be analyzed.
Time Frame: Baseline, 30, 60 days (end-of-treatment), 3, 6, 12 months
|
As measured by number of drinks per drinking day and percentage of days abstinent.
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Baseline, 30, 60 days (end-of-treatment), 3, 6, 12 months
|
Collaborators and Investigators
Investigators
- Study Director: Selvija G. Marovic, PhD, New York State Psychiatric Institute (NYSPI)
Publications and helpful links
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- NIAAA-HAS-14323
- NIH Grant R01 AA14323-01A1
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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