The Effect of Fruit and Fruit Juice on Plasma Total Antioxidant Capacity

The aim of the study is to compare the effect of consumption of a fruit beverage on plasma antioxidant capacity with that of the consumption of fruit.

Study Overview

• Status: Completed
• Conditions: Healthy
• Intervention / Treatment: Dietary supplement: Order 1; Dietary supplement: Order 2; Dietary supplement: Order 3; Dietary supplement: Order 4; Dietary supplement: Order 5; Dietary supplement: Order 6

• Study Type: Interventional
• Enrollment (Actual): 24
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Netherlands
  • Maastricht, Netherlands, 6229 ER
    • University of Maastricht

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Healthy males
• body mass index between 20-25

Exclusion Criteria:

• use of any medication
• smoking
• consumption of 3 or more glasses of alcohol per day
• involved in top sport

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: None (Open Label)

Number of Arms

6

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: 1	Dietary supplement: Order 1; Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands. Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 2	Dietary supplement: Order 2; Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands. Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 3	Dietary supplement: Order 3; Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands. Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 4	Dietary supplement: Order 4; Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands. Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 5	Dietary supplement: Order 5; Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands. Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.
Experimental: 6	Dietary supplement: Order 6; Supplement is fruit, fruit salad and fruit drink in different order. Fruit (two apples) Fruit salad, 400g (consist of apple, banana, orange, mandarin, pear, strawberry, grape, kiwi and melon) in amount relative to the popularity of the fruits consumed in the Netherlands. Fruit drink (fruit2day, strawberry/orange, 200ml) Each supplement is taken once, with one week wash out.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
The total plasma antioxidant capacity after intake of three different kinds of fruit(beverage)	3 weeks

Collaborators and Investigators

• Sponsor: Maastricht University Medical Center
• Investigators: Principal Investigator: Aalt Bast, Prof. Dr., Maastricht University

Study record dates

Study Major Dates

• Study Start: January 1, 2008
• Primary Completion (Actual): August 1, 2008
• Study Completion (Actual): November 1, 2008

Study Registration Dates

• First Submitted: October 11, 2007
• First Submitted That Met QC Criteria: October 16, 2007
• First Posted (Estimate): October 17, 2007

Study Record Updates

• Last Update Posted (Actual): February 24, 2017
• Last Update Submitted That Met QC Criteria: February 22, 2017
• Last Verified: July 1, 2009

More Information

Terms related to this study

• Keywords: Healthy subjects; antioxidant; fruit
• Other Study ID Numbers: MEC-07-3-043