Impact of Left Atrial Function on Postoperative Atrial Fibrillation

June 27, 2008 updated by: Florence Nightingale Hospital, Istanbul

Impact Of Velocity Vector Imaging, Tissue Doppler Imaging, Conventional Echocardiography And P Wave Dispertion In Evaluating Post-Operative Atrial Fibrillation After Coronary Bypass Graft Surgery

We aimed to demonstrate the impact of left atrial functions which were evaluated by three different echocardiographic modalities , on postoperative atrial fibrillation.

Study Overview

Status

Completed

Conditions

Detailed Description

Postoperative atrial fibrillation after coronary artery bypass greft operation (CABG) is major complication with a prevalence of 10-50%. Although the men mechanism is not known, in recent studies, age and left atrial function have been demonstrated as the most responsible factors. Velocity vector imaging (VVI) is a new modality which may give accurate and detailed information on both left atrial segmental and global function. In this study, our aim was to assess preoperative left atrial function by using three different echocardiographic modalities, VVI, tissue Doppler imaging and conventional echocardiography and evaluate the relation between the left atrial functions and the development of post-operative atrial fibrillation after CABG.

Study Type

Observational

Enrollment (Anticipated)

80

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey
      • Istanbul, Turkey, 34381
        • TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

30 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Tertiary care clinic

Description

Inclusion Criteria:

  • 1Coronary artery disease evidenced by coronary angiography
  • 2Patients with a decision of undergoing elective coronary artery bypass greft operation
  • 3Sinus rhythm in electrocardiography

Exclusion Criteria:

  • 1Rheumatic valve disease
  • 2Having prosthetic valve
  • 3CABG accompanied by other cardiac interventions (such as valvular surgery, ASD closure...etc)
  • 4Left ventricular l ejection fraction <40%
  • 5Mild to moderate mitral stenosis or regurgitation
  • 6Having atrial fibrillation or a history of atrial fibrillation attach during the last two weeks.
  • 7Congenital heart disease
  • 8Chronic liver disease
  • 9Chronic renal disease
  • 10Malignancy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
1
Patients with postoperative atrial fibrillation
2
Patients without postoperative atrial fibrillation.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Velocity vector imaging derived left atrial segmenter function, Tissue doppler derved left atrial segmenter function, conventional analysis of atrial function by 2D and pulsed wave echocardiography.
Time Frame: April 2008
April 2008

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Florence Nightingale Hospital, Istanbul

Investigators

  • Study Director: Saide Aytekin, Professor, T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2008

Primary Completion (Actual)

May 1, 2008

Study Completion (Actual)

May 1, 2008

Study Registration Dates

First Submitted

March 26, 2008

First Submitted That Met QC Criteria

March 28, 2008

First Posted (Estimate)

March 31, 2008

Study Record Updates

Last Update Posted (Estimate)

June 30, 2008

Last Update Submitted That Met QC Criteria

June 27, 2008

Last Verified

June 1, 2008

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • YT1977/2

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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