- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00669708
Topical Therapy With Cooling Effect in Dry Itchy Skin
February 1, 2010 updated by: University Hospital Muenster
kühlender Effekt Der Eucerin pH5 Lotion Und Der Eucerin pH5 Lotion Mit Cooling Compound Bei Trockener, Juckender Haut
Dry skin is a physiological condition and is characterized in contrast to greasy skin by roughness, desquamation and lack of brightness of the skin surface.
Subjectively, feelings of tension, burning and itching can occur.
The skin reacts more intensive on external and physical noxae.
Dry skin is caused by a lack of moisture.
This is most common during the winter months, when heating systems dry the air.
Bathing with hot water, spending extended periods of time in the hot sun, and the skin's natural aging process also remove moisture and oils from the skin.
It is diagnosed through clinical observation.
People suffering from dry skin often desire to improve this condition for optical cosmetic reasons and due to the occasional feeling of tension.
The aim of this investigation is to observe the improvement (or not) of dry itchy skin by a lotion containing a cooling compound
Study Overview
Status
Completed
Intervention / Treatment
Detailed Description
The patient use the lotion twice daily for a four-week period.
Additionally, the patient receives a documentation sheets to note several parameters.
In a sensory assessment, product specific parameter such as spreadability, permeability, lubricating, smell of lotion and cosmetic acceptance during the treatment will be assessed (at the beginning, after 2 weeks, after 4 weeks, 2 weeks after stopping treatment).
Before and after skin care measurement, the skin surface will be investigated by d-squames and corneometer.
After four weeks the skin care measurement will be terminated and the patient can continue with a treatment of his choice.
A monitoring of at least 70 patients is intended.
Study Type
Interventional
Enrollment (Anticipated)
70
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
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Münster, Germany, 48149
- Department of Dermatology, University of Münster
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Patients age: over 18 years
- itch over VAS 3
Exclusion Criteria:
- pregnancy, lactating women
- drug abuse
- active psychosomatic and psychiatric disease
- active cancer.
- topical application of tacrolimus, pimecrolimus, corticosteroids or capsaicin two weeks before study start
- intake of antihistamines, corticosteroids, cyclosporine A and other immunosuppressants, naltrexone, UV-therapy two weeks before study start
- participation in any other research study during the previous 4 weeks.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Active Comparator: 1
ph5 Eucerin Lotion with cooling compound
|
application twice daily to the skin
Other Names:
|
Placebo Comparator: 2
ph5 Eucerin Lotion
|
application twice daily to the skin
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Compensate the roughness of the skin Compensate sensory symptoms
Time Frame: 4 weeks
|
4 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Sonja Ständer, MD, Department of Dermatology, University of Münster
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
April 1, 2008
Primary Completion (Actual)
February 1, 2010
Study Completion (Actual)
February 1, 2010
Study Registration Dates
First Submitted
April 22, 2008
First Submitted That Met QC Criteria
April 29, 2008
First Posted (Estimate)
April 30, 2008
Study Record Updates
Last Update Posted (Estimate)
February 2, 2010
Last Update Submitted That Met QC Criteria
February 1, 2010
Last Verified
February 1, 2010
More Information
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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