Influence of Protein Source on Satiety and Metabolism

March 21, 2012 updated by: Robert Benamouzig, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Dietary protein is the more satiating nutrient, however it is not clear whether satiety may be influenced by the nature of the protein. This study was designed to assess potential differences between protein sources on satiety and their relationship with digestive and metabolic kinetics.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

120

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Bobigny, France, 93
        • Centre de recherche sur volontaires

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 40 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • BMI between 25 and 30

Exclusion Criteria:

  • allergy to milk proteins

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Soy protein
Dietary supplement: Soy proteins-enriched diet
Subjects consume for 9 days a supplement of 30g/d of soy protein
Experimental: Casein
Dietary supplement: Casein-enriched diet
Subjects consume for 9 days a supplement of 30g/d of casein
Experimental: MSP
Dietary supplement: Milk soluble protein-enriched diet
Subjects consume for 9 days a supplement of 30g/d of milk soluble protein
Experimental: Casein/MSP
Dietary supplement: Casein and milk soluble proteins-enriched diet
Subjects consume for 9 days a supplement of 30g/d of a mix of casein and milk soluble protein

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
satiety
Time Frame: 7 days
7 days

Secondary Outcome Measures

Outcome Measure
Time Frame
hormonal profiles, digestive fluxes of nutrients, postprandial dietary N metabolism
Time Frame: 9 days
9 days

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Collaborators

National Research Agency, France

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2008

Primary Completion (Actual)

June 1, 2009

Study Completion (Actual)

November 1, 2010

Study Registration Dates

First Submitted

March 13, 2009

First Submitted That Met QC Criteria

March 13, 2009

First Posted (Estimate)

March 16, 2009

Study Record Updates

Last Update Posted (Estimate)

March 22, 2012

Last Update Submitted That Met QC Criteria

March 21, 2012

Last Verified

March 1, 2012

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • SURPROL

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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