Prevalence of Renal Artery Stenosis in Patients Referred for Cardiac Catheterization (RAS)

Prevalence of Renal Artery Stenosis in Patients Refered for Cardiac Catheterization to Heart Center Hospital in July-September 2008

All patients referred for coronary angiography will simultaneously be evaluated for renal artery stenosis and then stenosis more than 50% will be analyzed according to clinical conditions, risk factors and lab data.

Study Overview

• Status: Completed
• Conditions: Renal Artery Stenosis
• Intervention / Treatment: Procedure: angiography

Detailed Description

Renal Artery Stenosis (RAS) is a common finding in patients with generalized atherosclerosis. It is the cause of 15-20% of end stage renal disease in elderly patients. The prevalence of asymptomatic RAS in general population is unknown but it estimated to be 18% in 7th decade and more than 50% in the 8th. It is critical to find and manage the RAS before it's symptoms appear. The Gold standard for diagnosis of atherosclerotic arterial stenosis is angiography. In this study we will evaluate the prevalence, severity, location and related factors to renal artery stenosis in patients whom referred for coronary angiography in period of July-September in one of the most referral heart center in Iran, "The Tehran heart center" which is doing more than 50 coronary angiography daily.

• Study Type: Observational
• Enrollment (Actual): 146

Contacts and Locations

Study Locations

• Iran, Islamic Republic of
  • Tehran, Iran, Islamic Republic of
    • Tehran Heart Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients reffered to the Tehran Heart center for coronary angiography

Description

Inclusion Criteria:

• age more than 18 years

Exclusion Criteria:

• contraindication to contrast use
• not signing consent

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
A; patients with renal artery stenosis	Procedure: angiography; all patients undergoing coronary angiography with VISIPAQUE and if they had coronary stenosis then renal artery angiography will be done. the dose of contrast will be chosen according to renal function and clinical conditions which will be varied from 75 to 300 ml.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prevalence of Renal Artery Stenosis (RAS)		2 months
The Number of Patients With Renal Artery Stenosis	the prevalence of renal artery stenosis in patients with coronary artery disease	3months

Collaborators and Investigators

• Sponsor: Imam Khomeini Hospital
• Collaborators: Tehran Heart Center

Study record dates

Study Major Dates

• Study Start: July 1, 2008
• Primary Completion (Actual): September 1, 2008
• Study Completion (Actual): April 1, 2009

Study Registration Dates

• First Submitted: July 11, 2008
• First Submitted That Met QC Criteria: April 21, 2009
• First Posted (Estimate): April 22, 2009

Study Record Updates

• Last Update Posted (Estimate): May 13, 2011
• Last Update Submitted That Met QC Criteria: May 11, 2011
• Last Verified: April 1, 2009

More Information

Terms related to this study

• Keywords: Atherosclerosis; angiography; RAS(renal Artery Stenosis)
• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Arterial Occlusive Diseases; Kidney Diseases; Urologic Diseases; Pathological Conditions, Anatomical; Constriction, Pathologic; Renal Artery Obstruction
• Other Study ID Numbers: RAS001