Systolic Pressure Index in Assessing the Risk of Cardiovascular Events (IPS)

Interest of Measuring the Systolic Pressure Index in Assessing the Risk of Cardiovascular Events Peri-operatively in the Surgery, Settled Out of Cardiovascular Surgery

To investigate whether the presence of a Systolic pressure index (<0.9 or> 1.4) is a marker of risk of cardiovascular events after peri-operative high-risk surgery outside the cardiac and vascular surgery.

Study Overview

• Status: Completed
• Conditions: Cardio-vascular Events

• Study Type: Observational
• Enrollment (Anticipated): 504

Contacts and Locations

Study Locations

• France
  • Limoges, France, 87000
    • Explorations fonctionnelles vasculaires et angiologie (Hôpital Dupuytren)

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All patients from thoracic surgery, cardiovascular surgery and transplantation,urologic surgery, gastrointestinal surgery and orthopedic surgery services and coming to a preoperative anesthesia consultation are concerned with the study.

Description

Inclusion Criteria:

• age> 40 years
• surgery set :
• Visceral surgery: gastrectomy or colectomy, abdomino-perineal amputation, pancreatic surgery, liver surgery, esophageal surgery
• In urological surgery: nephrectomy, total prostatectomy, cystectomy
• In thoracic surgery: pneumonectomy, lobectomy
• In orthopedic surgery: total hip replacement and total knee prosthesis

Exclusion Criteria:

• pathology making it impossible to measure Systolic Pressure Index
• life expectancy less than 6 months
• emergency surgery

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Patients exposed; Patients with Systolic Pressure Index <0,9 ou >1,4.
Patients not exposed; Patients with Systolic Pressure Index >0,9 ou <1,4.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
It is a composite involving the following events: death, cardiovascular death, acute coronary syndrome, left cardiac decompensation, stroke, transient ischemic attack	day1, day 2, day 3, 1 month, 1 year

Secondary Outcome Measures

Outcome Measure	Time Frame
- for the short term increase in the length of hospitalization - for the long term: death, cardiovascular death, hospitalization for acute coronary syndrome, cardiac decompensation left, TIA, stroke, acute ischemia and ischemia critical member.	day1, day 2, day 3, 1 month, 1 year

Collaborators and Investigators

• Sponsor: University Hospital, Limoges
• Investigators: Principal Investigator: Philippe LACROIX, MD, University Hospital, Limoges

Study record dates

Study Major Dates

• Study Start: January 1, 2008
• Primary Completion (Actual): August 1, 2009
• Study Completion (Actual): September 1, 2009

Study Registration Dates

• First Submitted: June 22, 2009
• First Submitted That Met QC Criteria: June 22, 2009
• First Posted (Estimate): June 23, 2009

Study Record Updates

• Last Update Posted (Estimate): March 15, 2012
• Last Update Submitted That Met QC Criteria: March 14, 2012
• Last Verified: June 1, 2009

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Heart Murmurs; Systolic Murmurs
• Other Study ID Numbers: I07029