Effects Of A Computerized Working Memory Training Program On Attention, Working Memory, And Academics, In Adolescents With Severe ADHD/LD

Our primary aim is to determine whether a computerized working memory (WM) training program will help students with severe learning and attention problems, in terms of improving their WM. Additional aims are to determine whether the WM training will also result in improvements in the students' concentration and school work, and how long any beneficial effects will last (i.e., whether the students will continue to show improvements once the training program has stopped).

Study Overview

• Status: Completed
• Conditions: Attention Deficit Disorder With Hyperactivity; Learning Disorders
• Intervention / Treatment: Other: Cogmed Working Memory Training Program.; Other: Academy of Math; Other: Special Education/Individualized Tutoring

Detailed Description

We have established a collaborative partnership between OISE, HSC, OPDS, and JVS to evaluate the effectiveness of a WM training program when conducted in a school setting. To determine whether the WM training program does improve WM, attention, behaviour, and/or academic achievement, we will compare its effects to those expected to result from two other intervention programs that focus on academic skills only: 1) a computerized software program known to improve math skills (Academy of Math®); and 2) extra, individualized tutoring in an area of academic weakness supervised by a trained and experienced staff person. We will assess WM, related cognitive abilities, ADHD symptoms, academic achievement, before and after intervention, and also at 3- and 6-month follow-up to determine whether any improvements are sustained and increased after the training has finished.

• Study Type: Interventional
• Enrollment (Actual): 120
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Canada
  • Ontario
    • Milton, Ontario, Canada
      • Ontario Provincial and Demonstration Schools
    • Toronto, Ontario, Canada, M5G 1X8
      • The Hospital for Sick Children

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 12 years to 17 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• fulltime enrollment at one of the three English-language speaking OPDS schools
• confirmed diagnosis of a specific LD with or without comorbid ADHD
• IQ > 80 (based on WISC-IV)
• English as the primary spoken language

Exclusion Criteria:

• uncorrected sensory impairments (vision, hearing)
• severe comorbid mental health disorders requiring medications other than those used for ADHD or intensive treatment
• severe impairments in oral communication, impeding intelligibility of spoken responses

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Cogmed Working Memory Training Program	Other: Cogmed Working Memory Training Program.; This program includes a set of visual-spatial and auditory-verbal WM tasks presented via the computer (see Appendix 1 for a description of these tasks). All tasks involve: a) maintenance of simultaneous mental representations of multiple stimuli; b) unique sequencing of stimulus order in each trial; and c) progressive adaptation of difficulty level as a function of individual performance. Training will require about 30 minutes per day, 5 days per week, for 5-6 weeks: participants are required to complete 90 WM trials on each training day. Training plans are individualized and are modified according to performance, but the typical plan includes 13 tasks, with 15 trials of 8 tasks each day.
Active Comparator: Academy of Math® program	Other: Academy of Math; This is an established evidence-based program designed to help at-risk learners (Grades K-12) develop mathematical proficiency by incorporating a mastery-learning approach to foster conceptual understanding, computational fluency, and strategic competency across 10 mathematical subject areas. Training is will require about 30 minutes, 5 days per week, for the same duration as the WM program (5-6 weeks), with a counselor or teacher acting as the training aide.
Active Comparator: Special Education/Individualized Tutoring	Other: Special Education/Individualized Tutoring; Students in this group will receive an additional 30 minutes daily of individualized supplemental instruction in their area of greatest academic need.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
CANTAB Spatial Working Memory	15-20 min
Automated Working Memory Assessment Listening Recall	15-20 min

Secondary Outcome Measures

Outcome Measure	Time Frame
Teacher - Strengths and Weakness of ADHD-symptoms and Normal-behavior scale (SWAN)	5 min/student
Teacher - Children's Organizational Skills Scale	5 min/student
Wide Range Achievement Test 4 Progress Monitoring Version: word reading, spelling, sentence comprehension, math computation	10-15 min

Collaborators and Investigators

• Sponsor: The Hospital for Sick Children
• Collaborators: Children's Hospital of Eastern Ontario
• Investigators: Principal Investigator: Rosemary Tannock, MD, The Hospital for Sick Children, Toronto Canada

Study record dates

Study Major Dates

• Study Start: November 1, 2008
• Primary Completion (Actual): January 1, 2011
• Study Completion (Actual): January 1, 2012

Study Registration Dates

• First Submitted: June 29, 2009
• First Submitted That Met QC Criteria: June 29, 2009
• First Posted (Estimate): June 30, 2009

Study Record Updates

• Last Update Posted (Estimate): May 27, 2015
• Last Update Submitted That Met QC Criteria: May 25, 2015
• Last Verified: May 1, 2015

More Information

Terms related to this study

• Keywords: Pediatrics; Attention-Deficit Hyperactivity Disorder; Learning Disorder; Computerized Working Memory Training Program
• Additional Relevant MeSH Terms: Mental Disorders; Pathologic Processes; Nervous System Diseases; Neurologic Manifestations; Neurobehavioral Manifestations; Dyskinesias; Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Communication Disorders; Disease; Attention Deficit Disorder with Hyperactivity; Hyperkinesis; Learning Disabilities
• Other Study ID Numbers: 1000013779