The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance (MUresv)

June 1, 2011 updated by: Marywood University
The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

Measurements

  • blood laboratory parameters
  • cognitive assessment changes
  • body composition changes
  • vascular endothelial response

Study Type

Interventional

Enrollment (Actual)

44

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Pennsylvania
      • Scranton, Pennsylvania, United States, 18509
        • Marywood University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

45 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • men and women between 45 and 75 years of age
  • Normal heart rate and Blood pressure
  • Ability to use personal computer interface
  • Successful completion of physical activity readiness questionnaire

Exclusion Criteria:

  • Cardiovascular disease, uncontrolled hypertension, lung disease
  • inability to tolerate exercise
  • have taken grape related supplement in past 12 months
  • current use of drugs or dietary supplements to enhance exercise performance
  • allergy to wine, grape juice or grape seed supplements

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Placebo Comparator: Sugar Pill
Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.
Other: Placebo Comparator: Sugar Pill
Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.
Active Comparator: Dietary Supplement: resveratrol
Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.
Dietary supplement: resveratrol
Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Vascular function
Time Frame: 4 weeks, with option of additional 4 week treatment period
vascular response to stress will be measured using flow mediated dilation and ultrasound.
4 weeks, with option of additional 4 week treatment period

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Body fat percentage
Time Frame: 4 weeks, with optional additional 4 week treatment period
Body fat percentage will be measured using a DEXA scan.
4 weeks, with optional additional 4 week treatment period
inflammation biomarkers
Time Frame: 4 weeks, with optional additional 4 week treatment period
Fasting blood draw
4 weeks, with optional additional 4 week treatment period
cognitive function
Time Frame: 4 weeks, with optional additional 4 week treatment period
cognitive function will be assessed using a validated computer based assessment tool
4 weeks, with optional additional 4 week treatment period

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Marywood University

Investigators

  • Principal Investigator: James Smoliga, Ph.D., Marywood University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2010

Primary Completion (Anticipated)

June 1, 2011

Study Completion (Anticipated)

June 1, 2011

Study Registration Dates

First Submitted

November 17, 2010

First Submitted That Met QC Criteria

November 18, 2010

First Posted (Estimate)

November 19, 2010

Study Record Updates

Last Update Posted (Estimate)

June 2, 2011

Last Update Submitted That Met QC Criteria

June 1, 2011

Last Verified

June 1, 2011

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • MU Smoliga Resveratrol
  • 2RESMU194218 (Other Identifier: Marywood University)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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