Metabolomic in Critical Ill Patients

January 16, 2024 updated by: Giovanni Landoni, Università Vita-Salute San Raffaele

Analysis of blood, urinary, and intrathecal metabolites of critical ill patients will be checked for possible correlations between metabolomics patterns and patients' outcomes.

Study Overview

Status

Terminated

Conditions

Metabolomic

Study Type

Observational

Enrollment (Actual)

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Italy
- Mi
  - Milano, Mi, Italy, 20132
    - Università Vita-Salute San Raffaele

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

14 years to 95 years (Adult, Older Adult)

Accepts Healthy Volunteers

Sampling Method

Non-Probability Sample

Study Population

Critical ill patients

Description

Inclusion Criteria:

patients with severe left or right ventricular dysfunction undergoing cardiac surgery
patients undergoing ablation of ventricular tachycardia
patients with febrile neutropenia after chemotherapy or allogeneic transplant for haematological diseases
patients undergoing thoracoabdominal vascular surgery

Exclusion Criteria:

pregnant women
no written consent

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Observational Models: Cohort
Time Perspectives: Prospective

Number of groups / cohorts

Cohorts and Interventions

Group / Cohort
criticall ill patients

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Metabolomic patterns to identify poor outcome Time Frame: hospital stay (approximately two weeks)	hospital stay (approximately two weeks)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Università Vita-Salute San Raffaele

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 27, 2015

Primary Completion (Actual)

October 31, 2017

Study Completion (Actual)

April 6, 2023

Study Registration Dates

First Submitted

January 9, 2012

First Submitted That Met QC Criteria