- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01668212
Perifollicular Doppler in Natural Cycle In Vitro Fertilization
Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle.
The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.
Study Overview
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
-
-
Quebec
-
Montréal, Quebec, Canada, H4P 2S4
- Ovo Fertilité
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Patient with a natural In Vitro Fertilization cycle.
- Patient under 38 years old
- Body mass indice under 35
- Ovulatory cycles between 20-35 days
Exclusion Criteria:
- Patient with a stimulation In Vitro Fertilization cycle
- Patient with a naturalIn Vitro Fertilization cycle with egg donor
- Patient with a natural In Vitro Fertilization cycle with freezing embryo
- Smoking patient
- Diabetic patient
- Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator
- Body mass indice over 35
- Patient over 38 years old
- Patient without ovulation or cycle over 35 days
- Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
natural In Vitro Fertilization cycle
Patient doing following natural In Vitro fertilization cycle
|
Doppler Ultrasound
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Quality perifollicular doppler and quality of the oocyte
Time Frame: 2 weeks
|
The measurements are done twice; on days of induction and oocyte retrieval.
During the blood sample collection on the day of the induction, there is also a measurement of progesterone, estradiol and luteinizing hormone (LH).
|
2 weeks
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Delphine Delrieu, MD, Clinique OVO
Study record dates
Study Major Dates
Study Start
Primary Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- OVO-11-01
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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