Randomized Trial of Web-Delivered Acceptance Therapy for Smoking Cessation (WebQuit)
July 29, 2020 updated by: Fred Hutchinson Cancer Center
Randomized Trial of Web-Delivered Acceptance Therapy for Smoking Cessation
The goal of this study is to determine whether the ACT website provides higher quit rates than a current standard smoking cessation website.
Study Overview
Study Type
Interventional
Enrollment (Actual)
2637
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Washington
-
Seattle, Washington, United States, 98109
- Fred Hutchinson Cancer Research Center
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 99 years (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- age 18 or older
- smokes at least five cigarettes daily for at least past 12 months
- wants to quit in next 30 days
- willing to be randomly assigned to either group
- resides in US
- has at least weekly access to a high speed Internet connection and email
- willing and able to read in English
- not participating in other smoking cessation interventions (including our other intervention studies
- has never used the Smokefree.gov website
- willing to complete all three follow-up surveys
- provide email, phone, and mailing address
- provide contact information for two collaterals (e.g., relatives).
- does not have family, friends, or other household members participating
Exclusion Criteria:
- The exclusion criteria are the opposite of the inclusion criteria above.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: CBT
Cognitive Behavioral Therapy
|
Other Names:
|
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Experimental: ACT
Acceptance & Commitment Therapy
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Other Names:
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
30-day point prevalence abstinence
Time Frame: 12 month post randomization
|
No smoking in the past 30 days, as reported 12 month post treatment.
|
12 month post randomization
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
7-day, 24-hour, and 30-day point prevalence quit rates
Time Frame: 3 months, 6 months, and 12 months post treatment
|
12 months: 24-hour and 7-day point prevalence quit rates.
3 and 6 months: 24-hour, 7-day, and 30-day point prevalence quit rates.
Across 3, 6, and 12 month timepoints, the repeated 30-day point prevalence abstinence.
|
3 months, 6 months, and 12 months post treatment
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Jackson S, Brown J, Norris E, Livingstone-Banks J, Hayes E, Lindson N. Mindfulness for smoking cessation. Cochrane Database Syst Rev. 2022 Apr 14;4(4):CD013696. doi: 10.1002/14651858.CD013696.pub2.
- Watson NL, Heffner JL, Mull KE, McClure JB, Bricker JB. Comparing Treatment Acceptability and 12-Month Cessation Rates in Response to Web-Based Smoking Interventions Among Smokers Who Do and Do Not Screen Positive for Affective Disorders: Secondary Analysis. J Med Internet Res. 2019 Jun 19;21(6):e13500. doi: 10.2196/13500.
- Watson NL, Mull KE, Heffner JL, McClure JB, Bricker JB. Participant Recruitment and Retention in Remote eHealth Intervention Trials: Methods and Lessons Learned From a Large Randomized Controlled Trial of Two Web-Based Smoking Interventions. J Med Internet Res. 2018 Aug 24;20(8):e10351. doi: 10.2196/10351.
- Bricker JB, Sridharan V, Zhu Y, Mull KE, Heffner JL, Watson NL, McClure JB, Di C. Trajectories of 12-Month Usage Patterns for Two Smoking Cessation Websites: Exploring How Users Engage Over Time. J Med Internet Res. 2018 Apr 20;20(4):e10143. doi: 10.2196/10143.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 24, 2014
Primary Completion (Actual)
October 26, 2016
Study Completion (Actual)
December 31, 2019
Study Registration Dates
First Submitted
March 14, 2013
First Submitted That Met QC Criteria
March 14, 2013
First Posted (Estimate)
March 18, 2013
Study Record Updates
Last Update Posted (Actual)
July 31, 2020
Last Update Submitted That Met QC Criteria
July 29, 2020
Last Verified
December 1, 2019
More Information
Terms related to this study
Other Study ID Numbers
- 7859
- NCI-2019-06975 (Registry Identifier: NCI / CTRP)
- R01CA166646 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.