Impact of Chronic Air Pollution on Non-cystic Fibrosis Bronchiectasis

July 18, 2013 updated by: Dr. Lieven Dupont, Universitaire Ziekenhuizen KU Leuven
We aim at investigation the impact of chronic air pollution exposure on non-cystic fibrosis bronchiectasis outcome.

Study Overview

Status

Completed

Conditions

Detailed Description

  • Patient files will be search for time of death and cause of death.
  • Other variables will be collected: bacterial culture results, therapy, gender, age, etc.
  • These data will be linked with pollution data: trafic load, distance to major road, etc.

Study Type

Observational

Enrollment (Actual)

189

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Belgium
    • Vlaams-Brabant
      • Leuven, Vlaams-Brabant, Belgium, 3000
        • UZ Leuven

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patients with a HRCT diagnosis of bronchiectasis and do not have a diagnosis of cystic fibrosis. They also need to have typical bronchiectatic disease (recurrent infections and sputum).

Description

Inclusion Criteria:

  • HRCT diagnosis of bronchiectasis
  • recurrent infections or chronic sputum production
  • patients between 18 and 65 years old.

Exclusion Criteria:

  • Cystic Fibrosis
  • Tumoral disease
  • Traction bronchiectasis due to interstitial lung disease
  • patients older than 65 years or younger than 18 years at recruitment
  • COPD

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Death
Time Frame: 6 years
From June 2006 till October 2012, enrolled patients' medical file will be screened if death has occurred. If so, cause of death will be search for in the patients' file.
6 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universitaire Ziekenhuizen KU Leuven

Investigators

  • Principal Investigator: Lieven J Dupont, MD, PhD, UZ Leuven
  • Principal Investigator: Pieter C Goeminne, MD, UZ Leuven

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

June 1, 2006

Primary Completion (Actual)

October 1, 2012

Study Completion (Actual)

April 1, 2013

Study Registration Dates

First Submitted

July 18, 2013

First Submitted That Met QC Criteria

July 18, 2013

First Posted (Estimate)

July 23, 2013

Study Record Updates

Last Update Posted (Estimate)

July 23, 2013

Last Update Submitted That Met QC Criteria

July 18, 2013

Last Verified

July 1, 2013

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • NCFB chronic pollution

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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