Cardiac MRI in Ischemic Stroke Study (CaMriSS)

November 7, 2016 updated by: Karl Georg Haeusler, Charite University, Berlin, Germany
The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic stroke.

Study Overview

Status

Completed

Conditions

Detailed Description

Primary safety objective: Contrast medium-enhanced cardiac magnetic resonance imaging is safe in patients with acute ischemic stroke. Primary outcome: The diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging is comparable to transesophageal echocardiography in patients with acute ischemic stroke.

Study Type

Observational

Enrollment (Actual)

103

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Berlin, Germany, 12203
        • Charité, Universitätsmedizin Berlin, Campus Benjamin Franklin
      • Essen, Germany
        • Elisabeth Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Overall, 103 patients with acute ischemic stroke detected by brain magnetic resonance imaging will be enrolled.

Description

Inclusion Criteria:

  • Patients with acute ischemic stroke detected by brain magnetic resonance imaging.

Exclusion Criteria:

  • Known atrial fibrillation or cardiac source of embolism
  • Severe aphasia
  • Acute infection or chronic inflammation
  • Severe arteriosclerosis or stenosis of brain-supplying arteries
  • Contraindications for magnetic resonance imaging or transesophageal echocardiography.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke.
Time Frame: < 1 week after ischemic stroke
< 1 week after ischemic stroke

Secondary Outcome Measures

Outcome Measure
Time Frame
Rate of unrecognised myocardial infarction detected by late gadolinium-enhanced cardiac MRI in patients with acute ischemic stroke.
Time Frame: < 1 week after ischemic stroke
< 1 week after ischemic stroke

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Charite University, Berlin, Germany

Collaborators

Center for Stroke Research Berlin
Cardiology and Angiology, Elisabeth Hospital, Essen, Germany

Investigators

  • Study Chair: Prof. Matthias Endres, MD, Center for Stroke Research Berlin
  • Principal Investigator: Karl Georg Haeusler, MD, Center for Stroke Research Berlin

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2012

Primary Completion (Actual)

November 1, 2014

Study Completion (Actual)

November 1, 2014

Study Registration Dates

First Submitted

August 7, 2012

First Submitted That Met QC Criteria

August 6, 2013

First Posted (Estimate)

August 7, 2013

Study Record Updates

Last Update Posted (Estimate)

November 8, 2016

Last Update Submitted That Met QC Criteria

November 7, 2016

Last Verified

November 1, 2016

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • CaMriSS_CSB
  • EA4/073/10 (Other Identifier: Charité Ethics Committee)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Stroke

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

3
Subscribe