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Search clinical trials for: Imipenem

Total 80 results

NCT04493151

Not yet recruiting

Imipenem/Cilastatin/Relebactam PK in ECMO

Conditions: Sepsis
NCT04482569

Recruiting

Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/Cilastatin

Conditions: Bacterial Infections
NCT04310930

Recruiting

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Conditions: Pulmonary Disease Due to Mycobacteria (Diagnosis)
NCT04229498

Not yet recruiting

Comparison of Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae

Conditions: Bloodstream Infection
NCT04208763

Recruiting

A Randomized Controlled Trial Comparing Imipenem and Tigecycline Versus Imipenem and Tigecycline With GM-CSF for the Management of Spontaneous Bacterial Peritonitis Presenting With Septic Shock.

Conditions: Spontaneous Bacterial Peritonitis
NCT04196608

Recruiting

In Vitro Activity of Ceftolozane/Tazobactam and Imipenem/Relebactam in Clinical Isolates of Pseudomonas Aeruginosa and Enterobacterales Collected From Hematology and Oncology Patients

Conditions: Ceftolozane/Tazobactam; Imipenem/Relebactam; Hematology and Oncology
NCT04147221

Recruiting

Imipenem-Relebactam Pharmacokinetics in Augmented Renal Clearance

Conditions: Sepsis
NCT03969901

Recruiting

Safety, Tolerability, Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)

Conditions: Suspected or Documented Gram-negative Bacterial Infection
NCT03897582

Recruiting

Beta-Lactams Dosing In Pneumonia in ICU in Patients Treated by Continuous Renal Replacement Therapy: the BLIPIC Study

Conditions: Beta-lactam; Continuous Renal Replacement Therapy; Pneumonia; Antibiotic
NCT03894046

Recruiting

Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex

Conditions: Acinetobacter Baumannii-calcoaceticus Complex; Hospital-acquired Bacterial Pneumonia; Ventilator-associated Bacterial Pneumonia; Bacteremia; Colistin Resistant ABC
NCT03884881

Active, not recruiting

Second-generation Sequencing Guides the Treatment of Severe Pneumonia

Conditions: Pneumonia; Metagenomic Next Generation Sequencing
NCT03858387

Recruiting

PK/PD and Clinial Outcomes of Beta-lactams in ICU Patients

Conditions: Critical Illness; Bacterial Infections
NCT03790631

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring

Conditions: Beta-lactam Antibiotics; Therapeutic Drug Monitoring; Toxicity; Efficacy; Imipenem; Meropenem; Piperacillin; Flucloxacillin; Amoxicillin; Ceftazidime; Cefepime
NCT03776305

Active, not recruiting

Imipenem in Critically Ill Patients

Conditions: Critically Ill Patients With ECMO
NCT03776409

Completed

Safety and Efficacy of Vancomycin Plus Beta-lactams

Conditions: Critical Illness
NCT03733340

Unknown status

Antibacterial Prophylaxis vs no Prophylaxis for Hematological Malignancies Patients Before Allo-HSCT

Conditions: Antibacterial Prophylaxis; Hematological Malignancies; Allogenetic Hematopoietic Stem Cell Transplantation; Imipenem
NCT03678142

Completed

DetectAB - Detecting Antibiotics

Conditions: Antibiotic Drug Concentration in Sweat
NCT03625739

Recruiting

Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis

Conditions: Tuberculosis
NCT03583333

Recruiting

Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)

Conditions: Hospital-Acquired Bacterial Pneumonia; Ventilator-Associated Bacterial Pneumonia
NCT03543436

Recruiting

Temocillin Versus a Carbapenem as Initial Intravenous Treatment for ESBL Related Urinary Tract Infections

Conditions: Urinary Tract Infections
NCT03445195

Completed

Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections

Conditions: Complicated Urinary Tract Infection; Acute Pyelonephritis
NCT03310606

Recruiting

Serum and Peritoneal Concentration in Antibiotics During the Surgical Management of Peritonitis

Conditions: Peritonitis; Critical Illness
NCT03308214

Unknown status

The Analysis of Factors Influencing the Vd of Imipenem in Septic Shock Patients

Conditions: Septic Shock
NCT03293485

Completed

Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)

Conditions: Complicated Intra-abdominal Infection; Complicated Urinary Tract Infection
NCT03245879

Completed

Antibiotic Stewardship in Small Hospitals

Conditions: Inappropriate Prescribing; Antibiotic Stewardship; Anti-Bacterial Agents
NCT03237182

Recruiting

The Individualized M(X) Drug-resistant TB Treatment Strategy Study

Conditions: Tuberculosis, Multidrug-Resistant
NCT03230916

Active, not recruiting

A Pharmacokinetics Study of MK-7655A in Pediatric Participants With Gram-negative Infections (MK-7655A-020)

Conditions: Suspected or Documented Gram-negative Bacterial Infection
NCT03177720

Recruiting

Evaluation of Innovative Tools in Development of Antibiotics

Conditions: Pneumonia
NCT03159078

Recruiting

Polymyxin B Monotherapy vs Combination Therapy in Critically Ill Patients With Multi-drug Resistant Pathogens

Conditions: Trauma; Resistant Infection; Critical Illness
NCT03113344

Recruiting

Population Pharmacokinetics of Anti-infective Drugs in Children With Infectious Diseases

Conditions: Children; Infection
NCT03019965

Completed

Efficacy of Betalactam Antibiotics in Prolonged Infusion Compared to Intermittent in Pediatric Patients With Sepsis

Conditions: Sepsis
NCT03012360

Recruiting

Antimicrobial Treatment in Patients With Ventilator-associated Tracheobronchitis

Conditions: Mechanical Ventilation Complication; Critical Illness
NCT03008746

Recruiting

Pulmonary Microbiota in Patients With Chronic Obstructive Pulmonary Disease Colonized With P. Aeruginosa Resistant to Imipenem

Conditions: Chronic Obstructive Pulmonary Disease
NCT02971423

Completed

Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous ETX2514 Administered in Healthy Subjects

Conditions: Acinetobacter Baumannii Infection
NCT02897206

Completed

Imipenem Prophylaxis in Patients With Acute Pancreatitis

Conditions: Acute Pancreatitis
NCT02795949

Completed

Study on Reduced Antibiotic Treatment vs Broad Spectrum Betalactam in Patients With Bacteremia by Enterobacteriaceae

Conditions: Enterobacteriaceae Infections
NCT02683603

Completed

Effect of Aerosolised Colistin in Ventilator Associated Pneumonia

Conditions: Pneumonia, Ventilator-Associated
NCT02670239

Unknown status

Pharmacokinetics of Imipenem During Ex Vivo Lung Perfusion (EVLP)

Conditions: Lung Transplantation
NCT02616354

Unknown status

Preliminary Research On Two-step Dosing Of Imipenem/Cilastatin

Conditions: Sepsis
NCT02611271

Recruiting

Elimination of Antibiotics During Renal Replacement Therapy and Cytosorb Adsorptive Therapy

Conditions: Critical Illness; Sepsis; Acute Kidney Injury
NCT02533609

Active, not recruiting

Elimination of Antibiotics During Citrate-anticoagulated Continuous-veno-venous-haemodialysis

Conditions: Acute Kidney Injury; Bacterial Infection
NCT02493764

Completed

Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)

Conditions: Bacterial Pneumonia
NCT02474706

Terminated

Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli

Conditions: Urinary Tract Infections
NCT02452047

Completed

Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) Versus Colistimethate Sodium+Imipenem+Cilastatin in Imipenem-Resistant Bacterial Infection (MK-7655A-013)

Conditions: Bacterial Infections
NCT02321800

Completed

A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections

Conditions: Urinary Tract Infections
NCT02213783

Completed

Comparison of the Pharmacodynamics of Imipenem in Patients With Febrile Neutropenia

Conditions: Patients With Febrile Neutropenia
NCT02191475

Unknown status

Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock

Conditions: Abdominal Infection
NCT02149329

Completed

Short Versus Extended Antibiotic Treatment With a Carbapenem for High-risk Febrile Neutropenia in Hematology Patients With FUO

Conditions: Febrile Neutropenia; Hematological Malignancy
NCT02099240

Unknown status

Patients Response to Early Switch To Oral:Osteomyelitis Study

Conditions: Osteomyelitis
NCT01852630

Completed

Imipenem Versus Cefepime in Spontaneous Bacterial Peritonitis and to Evaluate the Risk Factors for Treatment Failure

Conditions: Spontaneous Bacterial Peritonitis