Cognitive Stimulation in Adolescents

August 22, 2016 updated by: Matthew Johnson, Johns Hopkins University

Cognitive Training in Adolescents During Treatment for Substance Use Disorders

The purpose of this study is to see if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking in adolescents and young adults who are being treated for substance use problems. The study will compare the effects of different versions of the computer tasks.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

87

Phase

  • Phase 2

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Maryland
      • Baltimore, Maryland, United States, 21229
        • Mountain Manor Treatment Center

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

14 years to 21 years (Child, Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • age 14-21
  • Diagnosis of substance use disorder (SUD) by DSM-IV criteria with marijuana as primary substance of abuse
  • eligible for intensive outpatient treatment

Exclusion Criteria:

  • Untreated psychiatric disorder that might make participation hazardous
  • Any condition associated with severe cognitive impairment

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Factorial Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: computerized tasks- adaptive
Behavioral: Computerized tasks
The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks.
Active Comparator: computerized tasks - nonadaptive
Behavioral: Computerized tasks
The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
working memory (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention

Secondary Outcome Measures

Outcome Measure
Time Frame
timeline follow back (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention
delay discounting (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention
Stroop (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention
reading comprehension (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention
emotion regulation (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention
Go-No Go (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention
Global Appraisal of Individual Needs (change from baseline)
Time Frame: expected within 2 weeks after intervention
expected within 2 weeks after intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Johns Hopkins University

Collaborators

National Institute on Drug Abuse (NIDA)

Investigators

  • Principal Investigator: Matthew W Johnson, PhD, Johns Hopkins University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

October 1, 2013

Primary Completion (Actual)

August 1, 2015

Study Completion (Actual)

August 1, 2015

Study Registration Dates

First Submitted

September 17, 2013

First Submitted That Met QC Criteria

September 19, 2013

First Posted (Estimate)

September 23, 2013

Study Record Updates

Last Update Posted (Estimate)

August 24, 2016

Last Update Submitted That Met QC Criteria

August 22, 2016

Last Verified

August 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • NA_00080023
  • R21DA034942 (U.S. NIH Grant/Contract)

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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