- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01976377
Mucin Glycosylating Enzymes in Head and Neck Cancers
Expression of Mucin Glycosylating Enzymes in Head and Neck Cancers and Its Correlation With Clinico-pathological Parameters.
Study Overview
Status
Detailed Description
Glycosylation is the most common post-translational modification of proteins. Aberrant glycosylation is the hallmark of most human cancers and affect many cellular properties, including cell proliferation, apoptosis, differentiation, transformation, migration and immune response.
Though widely explored in various human cancers, the role of mucin glycosylating enzymes in HNSCC has not been elucidated. Our aims is to analyze the expression patterns of mucin glycosylating enzymes in HNSCC tissues. Furthermore, we will correlate the expression levels of mucin glycosylating enzymes with clinical characteristics of HNSCC patients.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Locations
-
-
-
Taipei, Taiwan, 100
- Recruiting
- National Taiwan University
-
Contact:
- Mei-Chun Lin
- Phone Number: 886-978261268
- Email: b91401051@ntu.edu.tw
-
Contact:
- Pei-Jen Lou, MD, PhD
- Phone Number: 886-972651527
- Email: pjlou@ntu.edu.tw
-
Principal Investigator:
- Pei-Jen Lou, M.D, Ph.D
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Head and neck cancer patients receiving operation in National Taiwan University Hospital
Exclusion Criteria:
- Recurrence or non-operable patients
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
---|
Stage I, II, III, IV HNSCC
Stage I, II, III, IV HNSCC reveive treatment in NTUH
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Measure the expression of mucin glycosylating in head and neck cancer
Time Frame: 1~5 years after patient received surgery
|
1~5 years after patient received surgery
|
Collaborators and Investigators
Investigators
- Principal Investigator: Pei-Jen Lou, M.D, Ph.D, National Taiwan University Hospital
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 201307074RIND
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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