Clinical Outcome in Uveitis

February 25, 2021 updated by: Sue Lightman, Moorfields Eye Hospital NHS Foundation Trust

Clinical Outcome and Causes of Visual Loss in Uveitis

This study is aimed at investigating the long term clinical outcome of patients with uveitis.

Study Overview

Status

Completed

Conditions

Detailed Description

Patients will be included if they are treated for uveitis and have had repeat follow-up. Data will be gathered from the entire length of the patients follow-up.

The main outcome measures will be:

Change from baseline of Best corrected visual acuity (BCVA)at 10 years Causes of vision loss (≤6/15, VL) and severe vision loss (≤6/60, SVL) at 10 years Number of clinical visits at 10 years.

Study Type

Observational

Enrollment (Actual)

231

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United Kingdom
      • London, United Kingdom, EC1V 2PD
        • Moorfields Eye Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Patient data will be gathered from the uveitis clinic at Moorfields Eye Hospital.

Description

Inclusion Criteria:

  • Clinical Diagnosis of Uveitis.

Exclusion Criteria:

  • No follow-up data.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Uveitis
Patient with a clinical diagnosis of Uveitis.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Best Corrected Visual Acuity
Time Frame: up to 10 years
Recorded repeat best corrected visual acuity at intervals throughout the length of follow-up.
up to 10 years

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Causes of visual loss
Time Frame: First follow-up, years 1,2,5,10, Final follow-up
Record any ocular changes related to permanent visual loss under 6/12 and severe visual loss under 6/60.
First follow-up, years 1,2,5,10, Final follow-up

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Moorfields Eye Hospital NHS Foundation Trust

Investigators

  • Principal Investigator: Sue Lightman, PhD,FRCOphth, Moorfields Eye Hospital NHS Foundation Trust

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2011

Primary Completion (Actual)

December 1, 2018

Study Completion (Actual)

December 1, 2019

Study Registration Dates

First Submitted

November 3, 2013

First Submitted That Met QC Criteria

November 13, 2013

First Posted (Estimate)

November 14, 2013

Study Record Updates

Last Update Posted (Actual)

March 1, 2021

Last Update Submitted That Met QC Criteria

February 25, 2021

Last Verified

February 1, 2021

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • LIGS10201

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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