Effect of Folate Acid on Offspring Obesity

September 9, 2014 updated by: Xirong Guo, Nanjing Medical University

Mechanism of Folate Acid in Influencing Offspring Obesity During Pregnancy

The purpose of this study is to observe the effect of lack or excess of folic acid in first, second and third trimester on child birth weight, fat content and the secretion of metabolism related hormone, and clinical follow-up their offspring obesity.

Study Overview

Status

Unknown

Conditions

Study Type

Observational

Enrollment (Anticipated)

20000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Jiangsu
      • Nanjing, Jiangsu, China, 210004
        • Nanjing Maternal and Child Health Care Hospital Affiliated to Nanjing Medical University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 45 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Women with the early, mid and late pregnancy; Chilren

Description

Inclusion Criteria:

  • Pregnancy women
  • children
  • Chinese

Exclusion Criteria:

-

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
The level of folate acid of pregnancy women at first trimester
Time Frame: 12 weeks of pregnancy
12 weeks of pregnancy

Secondary Outcome Measures

Outcome Measure
Time Frame
The level of folate acid of pregnancy women at second trimester
Time Frame: 20-24 weeks of pregnancy
20-24 weeks of pregnancy
The level of folate acid of pregnancy women at third trimester
Time Frame: 28-40 weeks of pregnancy
28-40 weeks of pregnancy
The birth weight, fat content and metabolism related hormone secretion of their offspring
Time Frame: At birth
At birth
The weight, fat content and metabolism related hormone secretion of their offspring at one year old
Time Frame: One years old
One years old
The weight, fat content and metabolism related hormone secretion of their offspring at 3 years old
Time Frame: 3 years old
3 years old
The weight, fat content and metabolism related hormone secretion of their offspring at 5-7 years old
Time Frame: 5-7 years old
5-7 years old
The weight, fat content and the secretion of metabolism related hormone of offspring at 18 years old
Time Frame: 18 years old
18 years old

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Nanjing Medical University

Investigators

  • Principal Investigator: Xirong Guo, Dr., Nanjing Medical University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2013

Primary Completion (Anticipated)

May 1, 2015

Study Completion (Anticipated)

May 1, 2015

Study Registration Dates

First Submitted

September 2, 2014

First Submitted That Met QC Criteria

September 8, 2014

First Posted (Estimate)

September 10, 2014

Study Record Updates

Last Update Posted (Estimate)

September 11, 2014

Last Update Submitted That Met QC Criteria

September 9, 2014

Last Verified

September 1, 2014

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • NMU-530604-XG1

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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