Cognitive Training in Inpatient Treatment for Substance Use Disorders

July 25, 2016 updated by: Christian Hendershot, Centre for Addiction and Mental Health
This study examines whether computer tasks can improve memory and other cognitive functions among patients receiving inpatient treatment for substance use disorders.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Participants will complete cognitive training sessions on a regular basis during inpatient treatment. Alternate versions of the computer tasks will be compared in a randomized design. Primary and secondary outcomes will consist of changes in cognitive performance before and after the training period.

Study Type

Interventional

Enrollment (Actual)

111

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Canada
    • Ontario
      • Toronto, Ontario, Canada
        • Centre for Addiction and Mental Health

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 60 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Participants must be patients registered for inpatient treatment at the Centre for Addiction and Mental Health
  • Age 18-60
  • Fluency in English
  • Able to attend scheduled training sessions
  • Comfortable using a computer and mouse

Exclusion Criteria:

  • Severe cognitive impairment
  • Current or past psychosis or diagnosis of schizophrenia
  • Photosensitive epilepsy or history of seizures triggered by light
  • Legal mandate to attend treatment

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Experimental
Computerized cognitive training activities
Behavioral: Cognitive training activities
Training activities consist of computer tasks designed to improve memory and cognition. The intervention consists of 45-minute training sessions delivered regularly during inpatient treatment.
Behavioral: Inpatient psychosocial therapy
Group psychosocial therapy delivered in an inpatient setting.
Active Comparator: Control
Non-adaptive computerized cognitive training activities
Behavioral: Cognitive training activities
Training activities consist of computer tasks designed to improve memory and cognition. The intervention consists of 45-minute training sessions delivered regularly during inpatient treatment.
Behavioral: Inpatient psychosocial therapy
Group psychosocial therapy delivered in an inpatient setting.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Auditory memory capacity - WAIS Digit Span score
Time Frame: Baseline, 3 weeks
WAIS Digit Span score
Baseline, 3 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Auditory memory capacity - WAIS Letter-number sequencing score
Time Frame: Baseline to 3 weeks
WAIS Letter-number sequencing score
Baseline to 3 weeks
Visual memory capacity - WMS Spatial span score
Time Frame: Baseline to 3 weeks
WMS Spatial span score
Baseline to 3 weeks
Visual memory capacity - WMS Symbol span score
Time Frame: Baseline to 3 weeks
WMS Symbol span score
Baseline to 3 weeks
Training progress score - Cognitive progress indicator score
Time Frame: Baseline to 4 weeks
Cognitive progress indicator score
Baseline to 4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Centre for Addiction and Mental Health

Investigators

  • Principal Investigator: Christian Hendershot, PhD, Centre for Addiction and Mental Health

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2015

Primary Completion (Actual)

July 1, 2016

Study Completion (Actual)

July 1, 2016

Study Registration Dates

First Submitted

February 2, 2015

First Submitted That Met QC Criteria

February 4, 2015

First Posted (Estimate)

February 5, 2015

Study Record Updates

Last Update Posted (Estimate)

July 27, 2016

Last Update Submitted That Met QC Criteria

July 25, 2016

Last Verified

July 1, 2016

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 0422014

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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