Interstitial Lung Diseases in the Veterans Administration

Interstitial Lung Diseases in the Veterans Administration Health System - A Retrospective Description of Patient Characteristics, Management, and Outcomes

The primary objective of this research project is to describe the characteristics, diagnosis, management, and outcomes of patients with Interstitial Lung Disease (ILD) who received care at the Veteran's Administration Veterans Integrated Service Network (VISN) 6 Mid-Atlantic Health Care Network (VISN6) (includes North Carolina, Virginia and West Virginia) for up to 5 years.

Study Overview

• Status: Active, not recruiting
• Conditions: Interstitial Lung Disease

• Study Type: Observational
• Enrollment (Anticipated): 3000

Contacts and Locations

Study Locations

• United States
  • North Carolina
    • Durham, North Carolina, United States, 27705
      • Durham VA Medical Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

All adults with encounters at any VISN6 healthcare facility during specified time period

Description

Inclusion Criteria:

• Interstitial Lung Disease (ILD) ICD-9 code diagnosis 515.0 or 516.3

Exclusion Criteria:

• Inadequate documentation of patient receiving care for ILD in the health records

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Retrospective

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Interstitial Lung Disease; Patients will be identified from a specified 5 year period based on an International Classification of Diseases-9 (ICD-9) code diagnosis of Interstitial Lung disease (515) or Idiopathic Pulmonary Fibrosis (516.3). The patients will be obtained from the records of the Veterans Integrated Service Network (VISN) 6: VA Mid-Atlantic Health Care Network.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Prevalence of Interstitial Lung Disease in the VISN6 Veterans Administration Patient Population	up to 5 years
Prevalence of Idiopathic Pulmonary Fibrosis in the VISN6 Veterans Administration Patient Population	up to 5 years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Accuracy of ICD-9 Codes for diagnosis of Interstitial Lung Disease	Will compare the reported ICD-9 code diagnosis with the diagnosis made after chart review and re-interpretation of the lung imaging and pathology	up to 5 years
Frequency of ICD-9 code diagnosis of Interstitial Lung Disease and clinic consultation with a pulmonary provider		up to 5 years
Prevalence of Co-morbid Diabetes Mellitus with Interstitial Lung Disease	Compare the prevalence of diabetes with interstitial lung disease as compared to the prevalence of diabetes in the general VA population	up to five years

Collaborators and Investigators

• Sponsor: Robert Tighe
• Collaborators: Boehringer Ingelheim; Durham VA Medical Center
• Investigators: Principal Investigator: Robert M Tighe, MD, Duke University Department of Medicine and Durham VA Medical Center

Study record dates

Study Major Dates

• Study Start: July 1, 2016
• Primary Completion (Anticipated): November 1, 2022
• Study Completion (Anticipated): June 1, 2023

Study Registration Dates

• First Submitted: June 19, 2015
• First Submitted That Met QC Criteria: June 22, 2015
• First Posted (Estimate): June 24, 2015

Study Record Updates

• Last Update Posted (Actual): July 26, 2022
• Last Update Submitted That Met QC Criteria: July 25, 2022
• Last Verified: July 1, 2022

More Information

Terms related to this study

• Keywords: Mortality; Hospitalization; Computed Tomography; Idiopathic Pulmonary Fibrosis; Interstitial Lung Disease; Electronic Health Records; Acute care visits; Anti-inflammatory drug therapies
• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Lung Diseases; Lung Diseases, Interstitial
• Other Study ID Numbers: 01882