Effects on Respiratory Patterns and Patient-ventilator Synchrony Using Pressure Support Ventilation

Effects on Respiratory Patterns and Patient-ventilator Synchrony in Different Ventilator Using Pressure Support Ventilation

Pressure Support Ventilation use Expiratory triggering sensitivity(Esense) to transfer inspiration to expiration,the value of Esense is fixed.That may lead to asynchrony between humans and ventilators,making people uncomfortable and prolonging weaning time.Some ventilators have auto cycle function Based on curves of pressure on respiratory patterns,it will make the transforming more synchrony with humans.Our prospective observational study will prove the superiority of the auto cycle function.

Study Overview

• Status: Unknown
• Conditions: Acute Respiratory Distress Syndrome; COPD; Post Operative

Detailed Description

From August 31st 2016 to August 31st 2017, all ARDS 、COPD and postoperative patients admitted to the ICUs will be enrolled. The demographic characteristics, diagnosis, formerly medical history, Ventilator indications, Ventilator data, other respiratory treatments, weaning outcome and 28 day mortality will be recorded

• Study Type: Observational
• Enrollment (Anticipated): 45

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 85 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

mechanical ventilation adult people using PSV mode in ICU

Description

Inclusion Criteria:

ARDS,COPD and Postoperative patient

Exclusion Criteria:

variety of reasons can not be placed next to the bed by the nasal EAdi catheter

Study Plan

How is the study designed?

Number of groups / cohorts

7

Cohorts and Interventions

Group / Cohort
E5 Esense 10%; PSV mode using E5 ventilator with Esense 10%
E5 Esense 30%; PSV mode using E5 ventilator with Esense 30%
E5 Esense 50%; PSV mode using E5 ventilator with Esense 50%
Servo-I Esense 10%; PSV mode using Servo-I ventilator with Esense 10%
Servo-I Esense 30%; PSV mode using Servo-I ventilator with Esense 30%
Servo-I Esense 50%; PSV mode using Servo-I ventilator with Esense 50%
E5 Esense autocycle; PSV mode using E5 ventilator with Esense Auto cycle

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
patient-ventilator synchrony using PSV mode between different ventilator for 180mins	180mins after the patients involved

Secondary Outcome Measures

Outcome Measure	Time Frame
Patient Respiratory Patterns during Pressure Support Ventilation for 180mins	180mins
Patient gas exchange during Pressure Support Ventilation for 180mins	180mins
Effects on Respiratory Patterns in different Expiratory triggering sensitivity for 180mins	180mins
work of triggering and respiratory in different Expiratory triggering sensitivity for 180mins	180mins

Collaborators and Investigators

• Sponsor: Southeast University, China

Study record dates

Study Major Dates

• Study Start: September 1, 2016
• Primary Completion (Anticipated): August 1, 2017
• Study Completion (Anticipated): August 1, 2017

Study Registration Dates

• First Submitted: July 30, 2016
• First Submitted That Met QC Criteria: August 23, 2016
• First Posted (Estimate): August 29, 2016

Study Record Updates

• Last Update Posted (Estimate): September 13, 2016
• Last Update Submitted That Met QC Criteria: September 10, 2016
• Last Verified: September 1, 2016

More Information

Terms related to this study

• Keywords: Pressure Support Ventilation; Synchrony
• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Respiration Disorders; Lung Diseases; Infant, Newborn, Diseases; Lung Injury; Infant, Premature, Diseases; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Acute Lung Injury
• Other Study ID Numbers: zhongdayiyuanICU

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED