Post-prandial Glucose Response From Phytochemical Rich Potato Products

January 16, 2018 updated by: Richard Mattes, Purdue University
Assess the impact of high antioxidant potato products on postprandial glycemic response and subsequent appetite and food intake.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Preliminary results from anthocyanin rich potato products suggest that a reduced postprandial glycemic response might be expected from certain types of potato products and that phenolic antioxidants may play a critical role in predicting the physiological response from potato products. Further, if consumed early in the day, such as at breakfast, a reduced glycemic response may serve to mitigate appetite and food consumption later in the day. Investigators aim to better understand how characteristics of commercial potato products (i.e. frozen potato products) with different phenolic profiles and content, may alter postprandial glycemic response and subsequent appetitive behavior. Specifically, investigators will assess the glycemic response from a serving of potato products in the morning using continuous glucose monitoring. Further, appetite and subsequent food consumption later in the day will be assessed through appetite logs and continuous glucose monitoring.

Study Type

Interventional

Enrollment (Actual)

24

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Indiana
      • West Lafayette, Indiana, United States, 47906
        • Purdue University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 50 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • BMI 18.5-25, male or female

Exclusion Criteria:

  • BMI outside 18.5-25

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Experimental: A
Skin On French Fry - breakfast Skin On French Fry - lunch Mashed Potatoes - dinner
Other: Skin On French Fry
Skin On French Fries will be provided at breakfast and lunch
Experimental: Experimental: B
Skin Off French Fry - breakfast Skin Off French Fry - lunch Mashed Potatoes - dinner
Other: Skin Off French Fry
Skin Off French Fries will be provided at breakfast and lunch
Experimental: Experimental: C
Hash brown - breakfast Hash brown - lunch Mashed Potato - dinner
Other: Hash brown
Hash brown potatoes will be provided at breakfast and lunch.
Experimental: Experimental: D
Pancake - breakfast Pretzels - lunch Macaroni - dinner
Other: Carbohydrate control
A pancake will be provided at breakfast, and pretzels will be provided at lunch.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in Blood Glucose over 24 hours
Time Frame: 24 hours
Samples taken every 5 minutes for 24 hours by a continuous glucose monitor
24 hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Appetite
Time Frame: Every hour for 24 hours
Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on the same day as the feeding intervention
Every hour for 24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Purdue University

Collaborators

USDA Beltsville Human Nutrition Research Center

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 31, 2017

Primary Completion (Actual)

June 25, 2017

Study Completion (Actual)

June 25, 2017

Study Registration Dates

First Submitted

February 21, 2017

First Submitted That Met QC Criteria

February 23, 2017

First Posted (Actual)

February 28, 2017

Study Record Updates

Last Update Posted (Actual)

January 18, 2018

Last Update Submitted That Met QC Criteria

January 16, 2018

Last Verified

January 1, 2018

More Information

Terms related to this study

Other Study ID Numbers

  • 055-046

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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