The Extreme Significance of Bilateral Embolic Retinal Phenomena That Can be Life Saving

Bilateral Retinal Embolic Phenomena Always Necessitates Immediate and Intensive Investigation. Careful, Documented, Ophthalmic Examination is All we Require to Initiate Life Saving Investigations.

This study shows how careful ophthalmic examination of two patients showed signs of simultaneous bilateral retinal emboli. Starting from this point significant, life threatening, underlying reasons were found and treated.

Study Overview

• Status: Completed
• Conditions: Life Threatening Diseases; Embolic Shower
• Intervention / Treatment: Diagnostic test: imaging

Detailed Description

Two patients were found to have signs of simultaneous bilateral retinal emboli. One patient was asymptomatic and routine ophthalmic examination showed bilateral retinal hemorrhages and exudates close to both optic discs. This patient was on anti-coagulant treatment for atrial fibrillation. The finding of bilateral signs of retinal emboli necessitated immediate blood tests and dose adjustments of her medication.

The second case did not have general symptoms other than mild evening chills and her eye examination again was the start point of intensive investigation to find the reason of her bilateral retinal emboli. Ultrasound studies revealed a life threatening reason that was urgently treated.

• Study Type: Observational
• Enrollment (Actual): 2

Contacts and Locations

Study Locations

• Canada
  • Alberta
    • Edmonton, Alberta, Canada, T5R5W9
      • Dr. S.S. Michel Clinic

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 30 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

any patient in which signs of bilateral retinal emboli are seen and documented (imaged).

Description

Inclusion Criteria:

• any patient who is found to have sure signs of bilateral retinal emboli.

Exclusion Criteria:

• all other bilateral retinal diseases.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The extreme significance of immediate investigation of cases of bilateral retinal emboli (non-diabetic bilateral posterior pole retinal nerve fiber or pre-retinal hemorrhages).	Patients that are noticed to have signs of bilateral retinal emboli (bilateral retinal nerve fiber layer hemorrhages or bilateral pre-retinal hemorrhages and sometimes bilateral soft exudates) may be asymptomatic or have very mild symptoms. However these patients must be immediately and, if needed, intensively investigated to find the source of these emboli. The extremely important point of this study is these patients usually have life threatening conditions that should be found out and treated in time.	through study completion, an average of one year

Collaborators and Investigators

• Sponsor: Dr. Shawkat Michel
• Investigators: Principal Investigator: shawkat s. Michel, MD, FRCS Ed, Dr. S.S. Michel Clinic, 214 MHC, 156 street and 87 Ave, Edmonton, AB, Canada

Study record dates

Study Major Dates

• Study Start (Actual): August 31, 2006
• Primary Completion (Actual): January 29, 2013
• Study Completion (Actual): December 31, 2018

Study Registration Dates

• First Submitted: March 6, 2017
• First Submitted That Met QC Criteria: March 8, 2017
• First Posted (Actual): March 13, 2017

Study Record Updates

• Last Update Posted (Actual): April 4, 2019
• Last Update Submitted That Met QC Criteria: April 2, 2019
• Last Verified: April 1, 2019

More Information

Terms related to this study

• Other Study ID Numbers: Bilateral retinal emboli

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: Color photographs of patients with bilateral retinal emboli and relevant medical conditions will be shared.
• IPD Sharing Time Frame: Color photographs are available from the time of publishing and until the end of 2018.
• IPD Sharing Access Criteria: Ophthalmologists interested may request the color photos by mail or email. Within four weeks from receiving request color photos will be sent

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No