- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03544307
Taekwondo Training and Postmenopausal Women With Stage-2 Hypertension
November 8, 2020 updated by: Sang-Ho Lee, Kosin University
Taekwondo Training Reduces Blood Catecholamine Levels and Arterial Stiffness in Postmenopausal Women With Stage-2 Hypertension
Aging is associated with hormonal imbalances and progressive decreases in arterial health and function.
It is crucial to prevent or reduce the negative effects of aging on hormonal balance and the vasculature by implementing appropriate lifestyle interventions, such as exercise training.
We examined the effects of a 12-week Taekwondo training program on blood catecholamines, arterial stiffness (pulse wave velocity, PWV), blood pressure (BP), resting heart rate, and muscular strength in postmenopausal women with stage 2 hypertension.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Using a parallel experimental design, participants were randomly assigned to either a Taekwondo exercise training group (n=10) or non-exercising control group (n=10) for 12 weeks.
Participant in the Taekwondo training group trained 3 days/week for 60 minutes per session, and the intensity progressed weekly. Participants in the control group performed no exercise intervention.
Study Type
Interventional
Enrollment (Actual)
20
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Nebraska
-
Omaha, Nebraska, United States, 68182
- University of Nebraska Omaha
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
65 years to 85 years (Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Description
Inclusion Criteria:
- Be diagnosed with stage-2 hypertension
- Be postmenopausal
- Be between 65 and 85 years old
Exclusion Criteria:
- Known cardiovascular, metabolic or renal diseases
- Physical limitations that prohibit exercise
- Participates in regular exercise
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Taekwondo Training
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks.
Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
|
Exercise group
|
|
No Intervention: Control
Sedentary control asked not to exercise
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
|
Blood Epinephrine Levels
Time Frame: 12-weeks
|
12-weeks
|
|
Blood Norepinephrine Levels
Time Frame: 12-weeks
|
12-weeks
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Arterial Stiffness
Time Frame: 12-weeks
|
Pulse Wave Velocity
|
12-weeks
|
|
Systolic Blood Pressure
Time Frame: 12-weeks
|
12-weeks
|
|
|
Hand Grip Strength
Time Frame: 12-weeks
|
12-weeks
|
|
|
Diastolic Blood Pressure
Time Frame: 12-weeks
|
12-weeks
|
|
|
Leg Strength
Time Frame: 12-weeks
|
12-weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Song Park, University of Nebraska
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 1, 2017
Primary Completion (Actual)
March 1, 2018
Study Completion (Actual)
March 1, 2018
Study Registration Dates
First Submitted
May 18, 2018
First Submitted That Met QC Criteria
May 18, 2018
First Posted (Actual)
June 1, 2018
Study Record Updates
Last Update Posted (Actual)
November 10, 2020
Last Update Submitted That Met QC Criteria
November 8, 2020
Last Verified
November 1, 2020
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- TaekwondoMenopause
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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