- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03607136
Early Detection of Disability and Health Promotion for Community-dwelling Elderly
Department of Physical Therapy, Tzu Chi University
Study Overview
Detailed Description
Physical inactivity can result in physical frailty and sarcopenia. Physical frailty and sarcopenia are two common and mostly overlapping geriatric conditions, which may cause negative consequences of aging, such as disability, hospitalization and mortality.
Regular physical activity has been suggested to maintain or improve functional capacity and body composition, as well as delay aging process. Nevertheless, inactivity prevalence still significantly increases among older adults, especially those with a disability. One of the probable reasons is that the use of physical activities or exercise interventions is not tailored to the needs and capabilities of the elderly.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- age greater than 50 years
- able to follow simple instructions
- willing to participate and sign consent form
Exclusion Criteria:
- unstable angina or epilepsy
- severe visual deficits
- cognitive dysfunction
- other musculoskeletal conditions that will limit mobility
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Non-Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: exercise training
Participants in the exercise training group received a 12-week exercise training.
|
Aerobic exercises, strengthening exercises, flexibility training for 60min, twice a week for 12 weeks
|
No Intervention: control
Participants in the control group did not receive any specific training programs instead of maintaining their usual activities of daily living.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Walking speed
Time Frame: Change from baseline at 12 weeks
|
Participants are asked to walk along a 14 m hallway.
The time taken to the middle 10 m is recorded to calculate walking speed (m/s).
|
Change from baseline at 12 weeks
|
Muscle strength
Time Frame: Change from baseline at 12 weeks
|
Muscle strength is assessed using hand-hold Dynamometers
|
Change from baseline at 12 weeks
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Timed up and go test
Time Frame: Change from baseline at 12 weeks
|
Participants are asked to stand up, walk 3 m, turn around a cone, and return to a sitting position
|
Change from baseline at 12 weeks
|
Walking endurance
Time Frame: Change from baseline at 12 weeks
|
Participants are asked to walk back and forth along a 20-meter corridor and to cover the maximum distance possible in six minutes
|
Change from baseline at 12 weeks
|
Sit-to-stand test
Time Frame: Change from baseline at 12 weeks
|
Participants are asked to stand up and sit down 5 times.
|
Change from baseline at 12 weeks
|
Berg balance scale
Time Frame: Change from baseline at 12 weeks
|
It consists of 14 items, including sitting unsupported, standing unsupported, standing with eyes closed, standing with feet together, standing on one foot, turning to look behind, retrieving objective from floor, random standing, reaching forward with an outsrptretched arm, sit to stand, stand to sit, transfer, turning 360 degrees, stool stepping, scored from 0 to 4, "0" indicates the lowest level of function and "4" the highest level of function.
Total Score = 56.
|
Change from baseline at 12 weeks
|
Gait kinematics
Time Frame: Change from baseline at 12 weeks
|
Gait kinematics are assessed by angular displacement of lower limbs using shoe-worn inertial measurement unit based device
|
Change from baseline at 12 weeks
|
Collaborators and Investigators
Study record dates
Study Major Dates
Study Start (Anticipated)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- IRB106-75-A-2
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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